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Journal of Molecular Biology|October 7, 2014
Structural and functional mechanisms of CRAC channel regulationAnn Hye-Ryong Shim, Leidamarie Tirado-Lee, Murali Prakriya
Proceedings of the National Academy of Sciences of the United States of America|December 19, 2009
Structural determinants of ion permeation in CRAC channelsBeth A McNally, Megumi Yamashita, Anita Engh, et al.
Journal of Immunology (Baltimore, Md. : 1950)|August 5, 2015
Store-Operated Ca2+ Release-Activated Ca2+ Channels Regulate PAR2-Activated Ca2+ Signaling and Cytokine Production in Airway Epithelial CellsAmit Jairaman, Megumi Yamashita, Robert P Schleimer, et al.
Nature|January 27, 2012
Gated regulation of CRAC channel ion selectivity by STIM1Beth A McNally, Agila Somasundaram, Megumi Yamashita, et al.
Journal of Immunology (Baltimore, Md. : 1950)|April 23, 2022
Extracellular Nucleotides and Histamine Suppress TLR3- and RIG-I-Mediated Release of Antiviral IFNs from Human Airway Epithelial CellsTimothy S Kountz, Assel Biyasheva, Robert P Schleimer, et al.
Scientific Reports|September 9, 2016
Allergens stimulate store-operated calcium entry and cytokine production in airway epithelial cellsAmit Jairaman, Chelsea H Maguire, Robert P Schleimer, et al.
The Journal of General Physiology|October 31, 2007
Orai1 mutations alter ion permeation and Ca2+-dependent fast inactivation of CRAC channels: evidence for coupling of permeation and gatingMegumi Yamashita, Laura Navarro-Borelly, Beth A McNally, et al.
The Journal of Physiology|April 25, 2013
The C- and N-terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channelsBeth A McNally, Agila Somasundaram, Amit Jairaman, et al.
Nature|August 22, 2006
Orai1 is an essential pore subunit of the CRAC channelMurali Prakriya, Stefan Feske, Yousang Gwack, et al.
Elife|October 30, 2020
A sulfur-aromatic gate latch is essential for opening of the Orai1 channel porePriscilla S-W Yeung, Christopher E Ing, Megumi Yamashita, et al.
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