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Science Signaling|February 17, 2026
Microglial reactivity and neuroinflammation-driven changes in motivational behaviors are regulated by Orai1 calcium channelsKaitlyn E DeMeulenaere, Rogan A Grant, Megan E Martin, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|December 16, 2010
The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signalingRyan P Hobbs, Evangeline V Amargo, Agila Somasundaram, et al.Nature Immunology|March 11, 2008
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and toleranceMasatsugu Oh-Hora, Megumi Yamashita, Patrick G Hogan, et al.Science Signaling|December 17, 2015
Depletion of H2S during obesity enhances store-operated Ca2+ entry in adipose tissue macrophages to increase cytokine productionGopal V Velmurugan, Huiya Huang, Hongbin Sun, et al.Neuron|November 4, 2023
The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytesBenayahu Elbaz, Alaa Darwish, Maia Vardy, et al.Nature Neuroscience|August 24, 2005
Activation of GPCRs modulates quantal size in chromaffin cells through G(betagamma) and PKCXiao-Ke Chen, Lie-Cheng Wang, Yang Zhou, et al.Nature|April 4, 2006
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel functionStefan Feske, Yousang Gwack, Murali Prakriya, et al.Journal of Immunology (Baltimore, Md. : 1950)|October 20, 2010
Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejectionChristie-Ann McCarl, Sara Khalil, Jian Ma, et al.Biorxiv : the Preprint Server for Biology|November 1, 2024
Syntaxin11 Deficiency Inhibits CRAC Channel Priming To Suppress Cytotoxicity And Gene Expression In FHLH4 Patient T LymphocytesSritama Datta, Abhikarsh Gupta, Kunal Mukesh Jagetiya, et al.Proceedings of the National Academy of Sciences of the United States of America|April 29, 2015
Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activationMate Maus, Amit Jairaman, Peter B Stathopulos, et al.Pageof 8