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Scientific Reports|December 29, 2019
C. elegans expressing D76N β<sub>2</sub>-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosisGiulia Faravelli, Sara Raimondi, Loredana Marchese, et al.Scientific Reports|September 18, 2020
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer's diseaseTatsuya Ikenoue, Francesco A Aprile, Pietro Sormanni, et al.Proceedings of the National Academy of Sciences of the United States of America|December 25, 2016
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's diseaseJohnny Habchi, Sean Chia, Ryan Limbocker, et al.Science Advances|March 3, 2016
An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's diseaseJohnny Habchi, Paolo Arosio, Michele Perni, et al.Communications Biology|January 5, 2021
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomersRodrigo Cataldi, Sean Chia, Katarina Pisani, et al.Pharmaceuticals (Basel, Switzerland)|December 28, 2021
Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's DiseaseMassimiliano Runfola, Michele Perni, Xiaoting Yang, et al.Science Advances|November 5, 2020
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's diseaseGabriella T Heller, Francesco A Aprile, Thomas C T Michaels, et al.Proceedings of the National Academy of Sciences of the United States of America|June 5, 2020
Rational design of a conformation-specific antibody for the quantification of Aβ oligomersFrancesco A Aprile, Pietro Sormanni, Marina Podpolny, et al.Journal of Neuroscience Methods|February 17, 2018
Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discoveryMichele Perni, Pavan K Challa, Julius B Kirkegaard, et al.Communications Biology|August 15, 2020
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanismRyan Limbocker, Benedetta Mannini, Francesco S Ruggeri, et al.Pageof 4