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Nucleic Acids Research|October 21, 2022
The Chemical Probes Portal: an expert review-based public resource to empower chemical probe assessment, selection and useAlbert A Antolin, Domenico Sanfelice, Alisa Crisp, et al.Journal of Biomolecular Screening|November 10, 2012
Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assayYvette Newbatt, Anthea Hardcastle, P Craig McAndrew, et al.Plos One|February 15, 2019
Tailored NEOadjuvant epirubicin, cyclophosphamide and Nanoparticle Albumin-Bound paclitaxel for breast cancer: The phase II NEONAB trial-Clinical outcomes and molecular determinants of responseCaitlin Murphy, Andrea Muscat, David Ashley, et al.British Journal of Pharmacology|January 19, 2005
Anxiogenic properties of an inverse agonist selective for alpha3 subunit-containing GABA A receptorsJohn R Atack, Peter H Hutson, Neil Collinson, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|July 8, 2005
In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202Florence I Raynaud, Steven R Whittaker, Peter M Fischer, et al.Cancer Research|March 5, 2022
Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer CellsNicola Lockwood, Silvia Martini, Ainara Lopez-Pardo, et al.Plos One|January 19, 2012
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signallingSimon R Stockwell, Georgina Platt, S Elaine Barrie, et al.Molecular Cancer Therapeutics|April 29, 2010
AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase that induces pharmacodynamic changes and inhibits human tumor xenograft growthKyla M Grimshaw, Lisa-Jane K Hunter, Timothy A Yap, et al.Molecules (Basel, Switzerland)|February 15, 2022
Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70Suzanne O'Connor, Yann-Vaï Le Bihan, Isaac M Westwood, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|March 2, 2016
Synthesis and Evaluation of a 2,11-Cembranoid-Inspired LibraryAmanda J Welford, John J Caldwell, Manjuan Liu, et al.Pageof 15