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Chemical Science|September 15, 2023
Selection of optimised ligands by fluorescence-activated bead sortingAlexandra R Paul, Mario Falsaperna, Helen Lavender, et al.The Biochemical Journal|February 21, 2002
Ecdysone-inducible expression of oncogenic Ha-Ras in NIH 3T3 cells leads to transient nuclear localization of activated extracellular signal-regulated kinase regulated by mitogen-activated protein kinase phosphatase-1David Plows, Paraskevi Briassouli, Carolyn Owen, et al.The EMBO Journal|March 19, 2005
Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressorSonia Rocha, Michelle D Garrett, Kirsteen J Campbell, et al.Cancer Research|September 20, 2006
Rare germ line CHEK2 variants identified in breast cancer families encode proteins that show impaired activationNayanta Sodha, Tine S Mantoni, Sean V Tavtigian, et al.Bioorganic & Medicinal Chemistry Letters|June 22, 2010
Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinasesThomas P Matthews, Tatiana McHardy, Suki Klair, et al.Molecular Cancer Therapeutics|January 8, 2010
The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106Michael I Walton, Paul D Eve, Angela Hayes, et al.Current Topics in Medicinal Chemistry|November 26, 2009
Fragment-based discovery of inhibitors of protein kinase BThomas G Davies, Steven J Woodhead, Ian CollinsExpert Opinion on Drug Discovery|April 19, 2013
Structure-based design, discovery and development of checkpoint kinase inhibitors as potential anticancer therapiesThomas P Matthews, Alan M Jones, Ian CollinsBioorganic & Medicinal Chemistry|May 4, 2011
Design and evaluation of 3-aminopyrazolopyridinone kinase inhibitors inspired by the natural product indirubinLynette A Smyth, Thomas P Matthews, Ian CollinsMethods in Molecular Biology (Clifton, N.J.)|July 12, 2017
Identifying and Validating Tankyrase Binders and Substrates: A Candidate ApproachKatie Pollock, Michael Ranes, Ian Collins, et al.Pageof 15