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ACS Medicinal Chemistry Letters|June 6, 2014
Benzofuran Derivatives as Potent, Orally Active S1P1 Receptor Agonists: A Preclinical Lead Molecule for MSAshis K Saha, Xiang Yu, Jian Lin, et al.ACS Medicinal Chemistry Letters|June 6, 2014
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1Lewis D Pennington, Kelvin K C Sham, Alexander J Pickrell, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5Victor J Cee, Mike Frohn, Brian A Lanman, et al.Bioorganic & Medicinal Chemistry Letters|November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activityLewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.Journal of Medicinal Chemistry|August 28, 2018
Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of MigraineDaniel B Horne, Kaustav Biswas, James Brown, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1)Brian A Lanman, Victor J Cee, Srinivasa R Cheruku, et al.Pageof 2