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Chemmedchem|August 11, 2022
The First Class of Small Molecules Potently Disrupting the YAP-TEAD Interaction by Direct CompetitionPascal Furet, Vincent Bordas, Mickaël Le Douget, et al.Journal of Medicinal Chemistry|September 23, 2011
Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinaseVito Guagnano, Pascal Furet, Carsten Spanka, et al.Journal of Medicinal Chemistry|March 4, 2026
Discovery of Clinical Candidate IAG933, a Potent YAP-TEAD PPI DisrupterMarkus Vögtle, Holger Sellner, Emilie Chapeau, et al.Chemmedchem|March 29, 2023
Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP-TEAD Protein-Protein Interaction InhibitorsHolger Sellner, Emilie Chapeau, Pascal Furet, et al.Cancer Discovery|September 25, 2012
FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitorVito Guagnano, Audrey Kauffmann, Simon Wöhrle, et al.Pageof 1