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Proceedings of the National Academy of Sciences of the United States of America|October 18, 2014
Activity-dependent FUS dysregulation disrupts synaptic homeostasisChantelle F Sephton, Amy A Tang, Ashwinikumar Kulkarni, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 9, 2014
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceAmanda N Sacino, Mieu Brooks, Michael A Thomas, et al.
Molecular Cancer Therapeutics|September 1, 2021
Functional Characterization of Brain Tumor-Initiating Cells and Establishment of GBM Preclinical Models that Incorporate Heterogeneity, Therapy, and Sex DifferencesCesar A Garcia, Adip G Bhargav, Mieu Brooks, et al.
EMBO Reports|August 8, 2020
Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin-deficient miceXiaolai Zhou, Mieu Brooks, Peizhou Jiang, et al.
Neuro-Oncology|June 15, 2026
Multi-sampling allows intra-tumoral heterogeneity querying and vulnerability profiling in glioblastomaDiogo Moniz Garcia, Wan-Hsin Lin, Daniel P Wickland, et al.
Molecular Neurodegeneration|April 24, 2025
Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal healthJolien Perneel, Miranda Lastra Osua, Sara Alidadiani, et al.
Molecular Genetics and Metabolism|November 28, 2017
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and courseNahid Tayebi, Loukia Parisiadou, Bahafta Berhe, et al.
Brain : a Journal of Neurology|June 7, 2020
Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategiesXiaolai Zhou, Alexandra M Nicholson, Yingxue Ren, et al.
Acta Neuropathologica Communications|June 2, 2018
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicityAlexandra M Nicholson, Xiaolai Zhou, Ralph B Perkerson, et al.
Brain Pathology (Zurich, Switzerland)|March 12, 2021
Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficitsRosa Rademakers, Alexandra M Nicholson, Yingxue Ren, et al.
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