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Mika Aoyagi-Scharber

Showing results (1-10 of 11) with videos related to

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The Journal of Pharmacology and Experimental Therapeutics|March 12, 2015
Trapping Poly(ADP-Ribose) PolymeraseYuqiao Shen, Mika Aoyagi-Scharber, Bing Wang
Plos One|July 7, 2018
Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidenceWyatt T Clark, G Karen Yu, Mika Aoyagi-Scharber, et al.
Journal of Medicinal Chemistry|December 15, 2015
Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer AgentBing Wang, Daniel Chu, Ying Feng, et al.
Acta Crystallographica. Section F, Structural Biology Communications|September 9, 2014
Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinoneMika Aoyagi-Scharber, Anna S Gardberg, Bryan K Yip, et al.
Plos One|January 19, 2019
BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesisGouri Yogalingam, Amanda R Luu, Heather Prill, et al.
Molecular Therapy. Methods & Clinical Development|July 17, 2019
Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type BHeather Prill, Amanda Luu, Bryan Yip, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 5, 2015
Neutral endopeptidase-resistant C-type natriuretic peptide variant represents a new therapeutic approach for treatment of fibroblast growth factor receptor 3-related dwarfismDaniel J Wendt, Melita Dvorak-Ewell, Sherry Bullens, et al.
Plos One|January 3, 2025
Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse modelManuel E Lopez, Daniel Wendt, Roger Lawrence, et al.
Molecular Therapy. Methods & Clinical Development|July 1, 2017
Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B MiceMika Aoyagi-Scharber, Danielle Crippen-Harmon, Roger Lawrence, et al.
Drug Delivery and Translational Research|January 17, 2020
Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type BAnita Grover, Danielle Crippen-Harmon, Lacey Nave, et al.
Pageof 2

Showing results (1-10 of 11) with videos related to

Sort By:
Pageof 2
The Journal of Pharmacology and Experimental Therapeutics|March 12, 2015
Trapping Poly(ADP-Ribose) PolymeraseYuqiao Shen, Mika Aoyagi-Scharber, Bing Wang
Plos One|July 7, 2018
Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidenceWyatt T Clark, G Karen Yu, Mika Aoyagi-Scharber, et al.
Journal of Medicinal Chemistry|December 15, 2015
Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer AgentBing Wang, Daniel Chu, Ying Feng, et al.
Acta Crystallographica. Section F, Structural Biology Communications|September 9, 2014
Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinoneMika Aoyagi-Scharber, Anna S Gardberg, Bryan K Yip, et al.
Plos One|January 19, 2019
BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesisGouri Yogalingam, Amanda R Luu, Heather Prill, et al.
Molecular Therapy. Methods & Clinical Development|July 17, 2019
Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type BHeather Prill, Amanda Luu, Bryan Yip, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 5, 2015
Neutral endopeptidase-resistant C-type natriuretic peptide variant represents a new therapeutic approach for treatment of fibroblast growth factor receptor 3-related dwarfismDaniel J Wendt, Melita Dvorak-Ewell, Sherry Bullens, et al.
Plos One|January 3, 2025
Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse modelManuel E Lopez, Daniel Wendt, Roger Lawrence, et al.
Molecular Therapy. Methods & Clinical Development|July 1, 2017
Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B MiceMika Aoyagi-Scharber, Danielle Crippen-Harmon, Roger Lawrence, et al.
Drug Delivery and Translational Research|January 17, 2020
Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type BAnita Grover, Danielle Crippen-Harmon, Lacey Nave, et al.
Pageof 2