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Journal of the American Chemical Society|December 11, 2003
Potent small-molecule binding to a dynamic hot spot on IL-2Christopher D Thanos, Mike Randal, James A WellsBiochemistry|May 28, 2003
Discovery and characterization of cooperative ligand binding in the adaptive region of interleukin-2Jennifer Hyde, Andrew C Braisted, Mike Randal, et al.Journal of the American Chemical Society|May 8, 2003
Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tetheringDaniel A Erlanson, Robert S McDowell, Molly M He, et al.Bioorganic & Medicinal Chemistry Letters|September 24, 2009
Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elementsMichael K Ameriks, Frank U Axe, Scott D Bembenek, et al.Journal of Medicinal Chemistry|May 28, 2004
Integrating fragment assembly and biophysical methods in the chemical advancement of small-molecule antagonists of IL-2: an approach for inhibiting protein-protein interactionsBrian C Raimundo, Johan D Oslob, Andrew C Braisted, et al.Nature Structural & Molecular Biology|July 20, 2004
Allosteric inhibition of protein tyrosine phosphatase 1BChristian Wiesmann, Kenneth J Barr, Jenny Kung, et al.Proceedings of the National Academy of Sciences of the United States of America|February 13, 2003
Binding of small molecules to an adaptive protein-protein interfaceMichelle R Arkin, Mike Randal, Warren L DeLano, et al.Journal of Medicinal Chemistry|February 3, 2006
Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1Wenjin Yang, Wanli Lu, Yafan Lu, et al.Bioorganic & Medicinal Chemistry Letters|February 16, 2010
Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors: part 1Alice Lee-Dutra, Danielle K Wiener, Kristen L Arienti, et al.Biochemistry|March 17, 2009
Fragment-based discovery of nonpeptidic BACE-1 inhibitors using tetheringWenjin Yang, Raymond V Fucini, Bruce T Fahr, et al.Pageof 1