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The Journal of Biological Chemistry|August 23, 2014
Therapeutic molecules and endogenous ligands regulate the interaction between brain cellular prion protein (PrPC) and metabotropic glutamate receptor 5 (mGluR5)Laura T Haas, Mikhail A Kostylev, Stephen M Strittmatter
The Journal of Biological Chemistry|February 22, 2019
Systematic and standardized comparison of reported amyloid-β receptors for sufficiency, affinity, and Alzheimer's disease relevanceLevi M Smith, Mikhail A Kostylev, Suho Lee, et al.
Biorxiv : the Preprint Server for Biology|November 24, 2025
Distinct Filament Conformation for Receptor-Bound Amyloid-ß from Alzheimer's Disease BrainMikhail A Kostylev, Carmen Butan, Graham P Roseman, et al.
Cerebral Cortex (New York, N.Y. : 1991)|July 2, 2016
Early Activation of Experience-Independent Dendritic Spine Turnover in a Mouse Model of Alzheimer's DiseaseJacqueline K Heiss, Joshua Barrett, Zizi Yu, et al.
Journal of the American Chemical Society|September 26, 2024
Cellular Prion Protein Conformational Shift after Liquid-Liquid Phase Separation Regulated by a Polymeric Antagonist and MutationsYangyi Liu, Marcus D Tuttle, Mikhail A Kostylev, et al.
Brain : a Journal of Neurology|December 16, 2015
Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's diseaseLaura T Haas, Santiago V Salazar, Mikhail A Kostylev, et al.
Acta Neuropathologica|January 11, 2017
Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP networkHideyuki Takahashi, Zoe A Klein, Sarah M Bhagat, et al.
The Journal of Biological Chemistry|May 29, 2015
Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse ModelsMikhail A Kostylev, Adam C Kaufman, Haakon B Nygaard, et al.
Alzheimer'S Research & Therapy|May 7, 2015
Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer's disease mouse modelHaakon B Nygaard, Adam C Kaufman, Tomoko Sekine-Konno, et al.
Nature Neuroscience|July 24, 2012
Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neuronsJi Won Um, Haakon B Nygaard, Jacqueline K Heiss, et al.
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