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Molecular and Cellular Neurosciences|March 20, 2024
Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregatesAnne-Line Strange Laursen, Mikkel Vestergaard Olesen, Jonas Folke, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 16, 2025
MTA-cooperative PRMT5 inhibitors from cofactor-directed DNA-encoded library screensJan Andersson, Sanne Cowland, Mikkel Vestergaard, et al.
Molecular Pharmacology|May 18, 2018
Small-Molecule Positive Allosteric Modulators of the <i>β</i><sub>2</sub>-Adrenoceptor Isolated from DNA-Encoded LibrariesSeungkirl Ahn, Biswaranjan Pani, Alem W Kahsai, et al.
Acta Neuropathologica Communications|June 13, 2026
α-Synuclein overexpression increases the tropism of pre-formed fibrils and MSA-patient derived seeds towards oligodendrogliaAnne-Line Strange Laursen, Frida Lind-Holm Mogensen, Jonas Folke, et al.
Journal of Medicinal Chemistry|March 18, 2025
From DNA-Encoded Library Screening to <b>AM-9747</b>: An MTA-Cooperative PRMT5 Inhibitor with Potent Oral In Vivo EfficacyIan Sarvary, Mikkel Vestergaard, Loris Moretti, et al.
Journal of Medicinal Chemistry|March 27, 2025
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of <i>MTAP</i>-Deleted CancersLiping H Pettus, Matthew Bourbeau, Nuria A Tamayo, et al.
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