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European Journal of Medicinal Chemistry|July 26, 2021
Substituted dienes prepared from betulinic acid - Synthesis, cytotoxicity, mechanism of action, and pharmacological parametersJan Pokorný, Denisa Olejníková, Ivo Frydrych, et al.
ACS Omega|March 24, 2025
Novel C-2 Aromatic Heterocycle-Substituted Triterpenoids Inhibit Hedgehog Signaling in GLI1 Overexpression Cancer CellsIvo Frydrych, Barbora Choma, Lucie Slavíková, et al.
European Journal of Medicinal Chemistry|May 6, 2015
Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cellsLucie Borkova, Lucie Jasikova, Jiri Rehulka, et al.
The Journal of Biological Chemistry|July 12, 2025
Triterpenoid derivatives inhibit Gli-mediated transcription in human glioblastoma cell line via direct interaction with Gli1Ivo Frydrych, Jiří Řehulka, Lucie Slavíková, et al.
European Journal of Medicinal Chemistry|September 29, 2022
Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugsJiří Hodoň, Ivo Frydrych, Zdeňka Trhlíková, et al.
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