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International Journal of Oncology|October 20, 2017
Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosisWishrawana S Ratnayake, André H Apostolatos, David A Ostrov, et al.
Oncology Letters|January 25, 2019
Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypesTracess Smalley, S M Anisul Islam, Christopher Apostolatos, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|December 8, 2019
Atypical Protein Kinase-C inhibitors exhibit a synergistic effect in facilitating DNA damaging effect of 5-fluorouracil in colorectal cancer cellsS M Anisul Islam, Avijit Dey, Rekha Patel, et al.
International Journal of Oncology|April 3, 2020
Simultaneous inhibition of atypical protein kinase‑C and mTOR impedes bladder cancer cell progressionRekha Patel, Sm Anisul Islam, Raja Reddy Bommareddy, et al.
The International Journal of Biochemistry & Cell Biology|February 15, 2011
A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastomaPrajit Pillai, Shraddha Desai, Rekha Patel, et al.
Cell Adhesion & Migration|November 13, 2018
The modulation of actin dynamics via atypical Protein Kinase-C activated Cofilin regulates metastasis of colorectal cancer cellsS M Anisul Islam, Rekha Patel, Raja Reddy Bommareddy, et al.
Cell Adhesion & Migration|February 2, 2021
Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasionWishrawana S Ratnayake, Christopher A Apostolatos, Sloan Breedy, et al.
Frontiers in Oncology|March 17, 2020
The Atypical Protein Kinase C Small Molecule Inhibitor ζ-Stat, and Its Effects on Invasion Through Decreases in PKC-ζ Protein ExpressionTracess Smalley, Rainer Metcalf, Rekha Patel, et al.
Medcomm|November 12, 2021
Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitusMini P Sajan, Barbara C Hansen, Mildred Acevedo-Duncan, et al.
Anti-Cancer Drugs|September 12, 2018
Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide: a potent protein kinase C-ι inhibitor as a potential prostate carcinoma therapeuticAndré H Apostolatos, Christopher A Apostolatos, Wishrawana S Ratnayake, et al.
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