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Cell Adhesion & Migration|May 22, 2018
Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitorsWishrawana S Ratnayake, Christopher A Apostolatos, André H Apostolatos, et al.
International Journal of Oncology|September 19, 2018
Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascadeAndré H Apostolatos, Wishrawana S Ratnayake, Hla Win-Piazza, et al.
International Journal of Molecular Sciences|April 17, 2025
Proteasome Inhibitor MG-132 and PKC-ι-Specific Inhibitor ICA-1S Degrade Mutant p53 and Induce Apoptosis in Ovarian Cancer Cell LinesMahfuza Marzan, Nuzhat Nowshin Oishee, Abigail Oluwafisayo Olatunji, et al.
Metabolism: Clinical and Experimental|January 10, 2012
Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ιMini P Sajan, Sonali Nimal, Stephen Mastorides, et al.
Molecules (Basel, Switzerland)|June 29, 2019
Investigation of the Anticancer Activity of Coordination-Driven Self-AssembledTwo-Dimensional Ruthenium Metalla-RectangleHarsh Vardhan, Ayman Nafady, Abdullah M Al-Enizi, et al.
Iscience|May 7, 2026
Progranulin deficiency in the brain activates an insulin signaling pathway that may promote neurodegenerationMini P Sajan, Geetika Aggarwal, Joel Jihwan Hwang, et al.
International Journal of Molecular Sciences|August 14, 2025
PKC-ι Regulates an Oncogenic Positive Feedback Loop Between the MAPK/JNK Signaling Pathway, c-Jun/AP-1 and TNF-α in Breast CancerNuzhat Nowshin Oishee, Mahfuza Marzan, Abigail Oluwafisayo Olatunji, et al.
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