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EMBO Molecular Medicine|July 30, 2016
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cellsLuca Sala, Zhiyi Yu, Dorien Ward-van Oostwaard, et al.
Biochemical and Biophysical Research Communications|October 13, 2015
Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposureGeorgios Kosmidis, Milena Bellin, Marcelo C Ribeiro, et al.
Circulation. Arrhythmia and Electrophysiology|October 28, 2016
Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Channel Gene SCN5AGeorgios Kosmidis, Christiaan C Veerman, Simona Casini, et al.
European Journal of Medicinal Chemistry|December 2, 2020
Targeting the K<sub>v</sub>11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivativesJacobus P D van Veldhoven, Giulia Campostrini, Constantijn J E van Gessel, et al.
Stem Cell Research|June 5, 2021
Generation of three human induced pluripotent stem cell lines, LUMCi024-A, LUMCi025-A, and LUMCi026-A, from two patients with combined oxidative phosphorylation deficiency 8 and a related controlRuben W J van Helden, Matthew J Birket, Christian Freund, et al.
Current Protocols|July 5, 2022
Software Tool for Automatic Quantification of Sarcomere Length and Organization in Fixed and Live 2D and 3D Muscle Cell Cultures In VitroJeroen M Stein, Ulgu Arslan, Marnix Franken, et al.
Nucleic Acids Research|December 5, 2019
Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nickingXiaoyu Chen, Francesca Tasca, Qian Wang, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|October 24, 2009
Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitorsAlessandra Moretti, Milena Bellin, Christian B Jung, et al.
Translational Research : the Journal of Laboratory and Clinical Medicine|April 27, 2023
Role of microRNAs in arrhythmogenic cardiomyopathy: translation as biomarkers into clinical practiceMireia Alcalde, Rocío Toro, Fernando Bonet, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 30, 2012
Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channelHongkang Zhang, Beiyan Zou, Haibo Yu, et al.
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