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Journal of Medicinal Chemistry
|
June 10, 2005
Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors
Clarence J Maring, Vincent S Stoll, Chen Zhao, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 3, 2011
Design, synthesis and structure-activity relationship of novel [3.3.1] bicyclic sulfonamide-pyrazoles as potent γ-secretase inhibitors
Danielle L Aubele, Anh P Truong, Darren B Dressen, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 15, 2013
Discovery of a novel [3.2.1] benzo fused bicyclic sulfonamide-pyrazoles as potent, selective and efficacious γ-secretase inhibitors
Xiaocong M Ye, Andrei W Konradi, Minghua Sun, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 17, 2013
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors
Raymond A Ng, Minghua Sun, Simeon Bowers, et al.
Journal of Medicinal Chemistry
|
February 5, 2019
Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma
Xiaojing Wang, Wesley Blackaby, Vivienne Allen, et al.
Journal of Medicinal Chemistry
|
May 30, 2013
Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over Notch
Gary Probst, Danielle L Aubele, Simeon Bowers, et al.
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Search research articles
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Showing results (41-50 of 46) with videos related to
Sort By:
Page
of 5
You have reached the last page of results.
This site can display upto 46 results.
Journal of Medicinal Chemistry
|
June 10, 2005
Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors
Clarence J Maring, Vincent S Stoll, Chen Zhao, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 3, 2011
Design, synthesis and structure-activity relationship of novel [3.3.1] bicyclic sulfonamide-pyrazoles as potent γ-secretase inhibitors
Danielle L Aubele, Anh P Truong, Darren B Dressen, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 15, 2013
Discovery of a novel [3.2.1] benzo fused bicyclic sulfonamide-pyrazoles as potent, selective and efficacious γ-secretase inhibitors
Xiaocong M Ye, Andrei W Konradi, Minghua Sun, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 17, 2013
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors
Raymond A Ng, Minghua Sun, Simeon Bowers, et al.
Journal of Medicinal Chemistry
|
February 5, 2019
Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma
Xiaojing Wang, Wesley Blackaby, Vivienne Allen, et al.
Journal of Medicinal Chemistry
|
May 30, 2013
Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over Notch
Gary Probst, Danielle L Aubele, Simeon Bowers, et al.
Page
of 5