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European Journal of Medicinal Chemistry
|
September 28, 2024
Design, synthesis and evaluation of novel LpxC inhibitors containing a hydrazone moiety as Gram-negative antibacterial agents
Fei Chen, Yufeng Jiang, Zidong Xu, et al.
Journal of Medicinal Chemistry
|
August 15, 2025
Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant <i>Staphylococcus aureus</i>
Meibo Duan, Xinyu Huang, Chuang Qiu, et al.
Journal of Medicinal Chemistry
|
February 24, 2026
Identification of 2,4-Diaminopyrimidine Derivatives as Novel Gut-Restricted Selective JAK1 Inhibitors for the Treatment of Inflammatory Bowel Disease
Hao Yue, Yu Bao, Jialong Xing, et al.
Bioorganic Chemistry
|
March 6, 2023
2-Aminopyrimidine derivatives as selective dual inhibitors of JAK2 and FLT3 for the treatment of acute myeloid leukemia
Sicong Xu, Yiran Zhu, Jie Meng, et al.
RSC Medicinal Chemistry
|
August 18, 2025
Design, synthesis, and biological evaluation of 5-chlorine-2-amino-pyrimidine derivatives as potent PLK4 inhibitors
Shuyi Mu, Wenqiang Sun, Zehui Qi, et al.
Bioorganic & Medicinal Chemistry
|
February 16, 2024
Discovery and optimization of dihydropteridone derivatives as novel PLK1 and BRD4 dual inhibitor for the treatment of cancer
Jiuyu Liu, Jingxuan Huang, Kang Wang, et al.
European Journal of Medicinal Chemistry
|
June 20, 2025
Rational design of CZL-S092: A novel indazole-based PLK4 inhibitor targeting neuroblastoma through virtual screening and fragment-based drug design strategies
Nian Liu, Ningyuan Hu, Cunzheng Fan, et al.
European Journal of Medicinal Chemistry
|
March 11, 2025
Discovery of novel dihydropteridone derivatives as orally bioavailable PLK1 inhibitors with reduced hERG inhibitory activity for acute myeloid leukemia treatment
Yunlei Hou, Shuang Li, Le Ren, et al.
Bioorganic Chemistry
|
May 25, 2024
Design, synthesis, and biological evaluation of 2,4-diaminopyrimidine derivatives as potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitors
Siyu Fu, Jiakuan Wei, Chunting Li, et al.
European Journal of Medicinal Chemistry
|
May 18, 2024
Novel biaryloxazolidinone derivatives with broad-spectrum antibacterial activity, favorable drug-like profiles and in vivo efficacy against linezolid-resistant Staphylococcusaureus
Meibo Duan, Chuang Qiu, Xinyu Huang, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 47) with videos related to
Sort By:
Page
of 5
European Journal of Medicinal Chemistry
|
September 28, 2024
Design, synthesis and evaluation of novel LpxC inhibitors containing a hydrazone moiety as Gram-negative antibacterial agents
Fei Chen, Yufeng Jiang, Zidong Xu, et al.
Journal of Medicinal Chemistry
|
August 15, 2025
Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant <i>Staphylococcus aureus</i>
Meibo Duan, Xinyu Huang, Chuang Qiu, et al.
Journal of Medicinal Chemistry
|
February 24, 2026
Identification of 2,4-Diaminopyrimidine Derivatives as Novel Gut-Restricted Selective JAK1 Inhibitors for the Treatment of Inflammatory Bowel Disease
Hao Yue, Yu Bao, Jialong Xing, et al.
Bioorganic Chemistry
|
March 6, 2023
2-Aminopyrimidine derivatives as selective dual inhibitors of JAK2 and FLT3 for the treatment of acute myeloid leukemia
Sicong Xu, Yiran Zhu, Jie Meng, et al.
RSC Medicinal Chemistry
|
August 18, 2025
Design, synthesis, and biological evaluation of 5-chlorine-2-amino-pyrimidine derivatives as potent PLK4 inhibitors
Shuyi Mu, Wenqiang Sun, Zehui Qi, et al.
Bioorganic & Medicinal Chemistry
|
February 16, 2024
Discovery and optimization of dihydropteridone derivatives as novel PLK1 and BRD4 dual inhibitor for the treatment of cancer
Jiuyu Liu, Jingxuan Huang, Kang Wang, et al.
European Journal of Medicinal Chemistry
|
June 20, 2025
Rational design of CZL-S092: A novel indazole-based PLK4 inhibitor targeting neuroblastoma through virtual screening and fragment-based drug design strategies
Nian Liu, Ningyuan Hu, Cunzheng Fan, et al.
European Journal of Medicinal Chemistry
|
March 11, 2025
Discovery of novel dihydropteridone derivatives as orally bioavailable PLK1 inhibitors with reduced hERG inhibitory activity for acute myeloid leukemia treatment
Yunlei Hou, Shuang Li, Le Ren, et al.
Bioorganic Chemistry
|
May 25, 2024
Design, synthesis, and biological evaluation of 2,4-diaminopyrimidine derivatives as potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitors
Siyu Fu, Jiakuan Wei, Chunting Li, et al.
European Journal of Medicinal Chemistry
|
May 18, 2024
Novel biaryloxazolidinone derivatives with broad-spectrum antibacterial activity, favorable drug-like profiles and in vivo efficacy against linezolid-resistant Staphylococcusaureus
Meibo Duan, Chuang Qiu, Xinyu Huang, et al.
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of 5