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Cancer Research|April 19, 2007
SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformationQingyang Gu, Mingjia Tan, Yi SunNeoplasia (New York, N.Y.)|January 28, 2015
Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalizationMingjia Tan, Hua Li, Yi SunOncogene|July 27, 2005
A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cellsKatrina M Bockbrader, Mingjia Tan, Yi SunResearch (Washington, D.C.)|July 11, 2025
E3 Ligase Rbx1 Orchestrates Thymus Development and Fate Determination of αβ-γδ T CellsDi Wu, Qiuxu Chen, Mingjia Tan, et al.Plos One|March 30, 2012
The p21-dependent radiosensitization of human breast cancer cells by MLN4924, an investigational inhibitor of NEDD8 activating enzymeDong Yang, Mingjia Tan, Gongxian Wang, et al.Radiation Research|February 6, 2023
Sag/Rbx2 Partial Inactivation Sensitizes Mice to Radiation and Radiation-Induced Tumorigenesis1Yi Sun, Hua Li, Mingjia Tan, et al.Translational Oncology|April 8, 2019
Inactivation of SAG or ROC1 E3 Ligase Inhibits Growth and Survival of Renal Cell Carcinoma Cells: Effect of BIMYu Wang, Mingjia Tan, Hua Li, et al.Scientific Reports|December 3, 2016
SAG/RBX2 E3 ligase complexes with UBCH10 and UBE2S E2s to ubiquitylate β-TrCP1 via K11-linkage for degradationPeng Kuang, Mingjia Tan, Weihua Zhou, et al.Molecular Cancer|December 14, 2016
Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axisMingjia Tan, Jie Xu, Javed Siddiqui, et al.Life Medicine|January 28, 2025
SHOC2 plays an oncogenic or tumor-suppressive role by differentially targeting the MAPK and mTORC1 signals in liver cancerXiahong You, Longyu Dou, Mingjia Tan, et al.Pageof 5