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Circulation Research|December 29, 2012
Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophyShouji Matsushima, Junya Kuroda, Tetsuro Ago, et al.
The Journal of Clinical Investigation|November 5, 2003
Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophyMitsutaka Yamamoto, Guiping Yang, Chull Hong, et al.
The Journal of Clinical Investigation|October 5, 2010
Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in miceDominic P Del Re, Takahisa Matsuda, Peiyong Zhai, et al.
Antioxidants & Redox Signaling|November 5, 2013
Aggregate-prone R120GCRYAB triggers multifaceted modifications of the thioredoxin systemSoumyajit Banerjee Mustafi, Julianne H Grose, Huali Zhang, et al.
Autophagy|June 25, 2025
NAD+ repletion restores cardioprotective autophagy and mitophagy in obesity-associated heart failure by suppressing excessive trophic signalingMahmoud Abdellatif, Francisco Vasques-Nóvoa, João Pedro Ferreira, et al.
Antioxidants (Basel, Switzerland)|August 6, 2021
β-Hydroxybutyrate, a Ketone Body, Potentiates the Antioxidant Defense via Thioredoxin 1 Upregulation in CardiomyocytesShin-Ichi Oka, Fan Tang, Adave Chin, et al.
JCI Insight|April 2, 2024
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout miceSatvik Mareedu, Nadezhda Fefelova, Cristi L Galindo, et al.
The Journal of Clinical Investigation|February 12, 2026
PPARα-NFκB heterodimer mediates obesity-induced diastolic dysfunction through autocrine production of IL-6Shin-Ichi Oka, Eun-Ah Sung, Peiyong Zhai, et al.
Cell Metabolism|November 8, 2011
PPARα-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathwayShinichi Oka, Ralph Alcendor, Peiyong Zhai, et al.
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