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Biochemical Pharmacology|December 13, 2022
Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell linesJing Gao, Chen Zhou, Yan Zhong, et al.
Biochemical and Biophysical Research Communications|October 14, 2019
Large conformation shifts of Vibrio cholerae VqmA dimer in the absence of target DNA provide insight into DNA-binding mechanisms of LuxR-type receptorsHai Wu, Minjun Li, Chao Peng, et al.
Nature Communications|May 9, 2025
Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitroHaixia Su, Guofeng Chen, Hang Xie, et al.
Journal of Synchrotron Radiation|January 19, 2024
Finback: a web-based data collection system at SSRF biological macromolecular crystallography beamlinesFeng Yu, Ke Liu, Huan Zhou, et al.
Journal of Medicinal Chemistry|May 28, 2020
Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based ApproachFubao Huang, Hangchen Hu, Kai Wang, et al.
Oxidative Medicine and Cellular Longevity|April 11, 2022
Propofol Upregulates MicroRNA-30b to Inhibit Excessive Autophagy and Apoptosis and Attenuates Ischemia/Reperfusion Injury In Vitro and in PatientsZhiqi Lu, Jiaojiao Shen, Xubin Chen, et al.
The Biochemical Journal|September 11, 2016
Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleDFeng Yu, Minjun Li, Chunyan Xu, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|April 7, 2025
Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L ProteaseHaixia Su, Guoqing Wu, Muya Xiong, et al.
Journal of Medicinal Chemistry|May 18, 2019
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis AgentXianglei Zhang, Guangyu Dong, Heng Li, et al.
International Journal of Biological Macromolecules|February 4, 2026
Crystallographic fragment screening discovers novel micromolar active inhibitors and druggable hotspots of SARS-CoV-2 PLproWei-Wei Wang, Li-Qing Huang, Qin Xu, et al.
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