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Human Mutation|January 30, 2009
A mutation in the signal sequence of LRP5 in a family with an osteoporosis-pseudoglioma syndrome (OPPG)-like phenotype indicates a novel disease mechanism for trinucleotide repeatsBoi-Dinh Chung, Hülya Kayserili, Minrong Ai, et al.Journal of the Endocrine Society|July 10, 2019
Long-Acting and Selective Oxytocin Peptide Analogs Show Antidiabetic and Antiobesity Effects in Male MiceBrandy Snider, Andrea Geiser, Xiao-Peng Yu, et al.Diabetes|May 2, 2022
GIPR Agonism Inhibits PYY-Induced Nausea-Like BehaviorRicardo J Samms, Richard Cosgrove, Brandy M Snider, et al.Science Advances|June 18, 2025
Hypophagia and body weight loss by tirzepatide are accompanied by fewer GI adverse events compared to semaglutide in preclinical modelsTito Borner, Allison M Pataro, Sarah A Doebley, et al.Diabetes, Obesity & Metabolism|January 9, 2026
GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian modelsCaitlin Baumer-Harrison, Danya Aldaghma, Alex D White, et al.Diabetes|August 12, 2021
GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist-Induced Nausea and Emesis in Preclinical ModelsTito Borner, Caroline E Geisler, Samantha M Fortin, et al.Science Translational Medicine|December 18, 2024
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipronKyle W Sloop, Amy L Cox, David B Wainscott, et al.Pageof 3