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Journal of Medicinal Chemistry|May 3, 2023
Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH2 Lead to Potent and Selective Agonists at hMC1R and hMC4RYang Zhou, Saghar Mowlazadeh Haghighi, Jonathon R Sawyer, et al.European Journal of Pharmacology|February 15, 2011
Utilize conjugated melanotropins for the earlier diagnosis and treatment of melanomaMinying Cai, Zhonglin Liu, Hongchang Qu, et al.Annals of the New York Academy of Sciences|July 10, 2003
Exploring the stereostructural requirements of peptide ligands for the melanocortin receptorsVictor J Hruby, Minying Cai, Paolo Grieco, et al.Biochemistry|September 12, 2009
Novel binding motif of ACTH analogues at the melanocortin receptorsYingkui Yang, Victor J Hruby, Min Chen, et al.European Journal of Pharmacology|May 17, 2020
Melanocortin 3 receptor activation with [D-Trp8]-γ-MSH suppresses inflammation in apolipoprotein E deficient miceJames J Kadiri, Keshav Thapa, Katja Kaipio, et al.ACS Pharmacology & Translational Science|October 19, 2020
Development of Ligand-Drug Conjugates Targeting Melanoma through the Overexpressed Melanocortin 1 ReceptorYang Zhou, Saghar Mowlazadeh Haghighi, Zekun Liu, et al.Journal of Medicinal Chemistry|March 18, 2005
Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analoguesMinying Cai, Alexander V Mayorov, Christopher Cabello, et al.Journal of Medicinal Chemistry|November 3, 2017
Design of MC1R Selective γ-MSH Analogues with Canonical Amino Acids Leads to Potency and PigmentationYang Zhou, Saghar Mowlazadeh Haghighi, Ioanna Zoi, et al.European Journal of Medicinal Chemistry|April 22, 2018
Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH2, leads to hMC1R selectivity and pigmentationSaghar Mowlazadeh Haghighi, Yang Zhou, Jixun Dai, et al.Peptides|May 8, 2007
Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5Paolo Grieco, Minying Cai, Guoxia Han, et al.Pageof 24