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Journal of Biochemistry|July 25, 2006
Fucose removal from complex-type oligosaccharide enhances the antibody-dependent cellular cytotoxicity of single-gene-encoded bispecific antibody comprising of two single-chain antibodies linked to the antibody constant regionAkito Natsume, Masako Wakitani, Naoko Yamane-Ohnuki, et al.Journal of Immunological Methods|October 21, 2005
Fucose removal from complex-type oligosaccharide enhances the antibody-dependent cellular cytotoxicity of single-gene-encoded antibody comprising a single-chain antibody linked the antibody constant regionAkito Natsume, Masako Wakitani, Naoko Yamane-Ohnuki, et al.Genes to Cells : Devoted to Molecular & Cellular Mechanisms|October 26, 2011
Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycansTsunehiro Mizushima, Hirokazu Yagi, Emi Takemoto, et al.Journal of Molecular Biology|March 21, 2007
Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1Shigeki Matsumiya, Yoshiki Yamaguchi, Jun-ichi Saito, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 6, 2006
Nonfucosylated therapeutic IgG1 antibody can evade the inhibitory effect of serum immunoglobulin G on antibody-dependent cellular cytotoxicity through its high binding to FcgammaRIIIaShigeru Iida, Hirofumi Misaka, Miho Inoue, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 17, 2007
A nonfucosylated anti-HER2 antibody augments antibody-dependent cellular cytotoxicity in breast cancer patientsEiji Suzuki, Rinpei Niwa, Shigehira Saji, et al.Cancer Research|May 17, 2008
Engineered antibodies of IgG1/IgG3 mixed isotype with enhanced cytotoxic activitiesAkito Natsume, Mika In, Hiroyuki Takamura, et al.Glycobiology|January 10, 2016
Comparison of biological activities of human antithrombins with high-mannose or complex-type nonfucosylated N-linked oligosaccharidesTsuyoshi Yamada, Yutaka Kanda, Makoto Takayama, et al.International Journal of Oncology|April 20, 2011
Overexpression of α1,6-fucosyltransferase in hepatoma enhances expression of Golgi phosphoprotein 2 in a fucosylation-independent mannerSayuri Kawamoto, Kenta Moriwaki, Tsutomu Nakagawa, et al.Journal of Biotechnology|June 15, 2007
Establishment of a GDP-mannose 4,6-dehydratase (GMD) knockout host cell line: a new strategy for generating completely non-fucosylated recombinant therapeuticsYutaka Kanda, Harue Imai-Nishiya, Reiko Kuni-Kamochi, et al.Pageof 4