Moataz A Shaldam - JoVE Visualize

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Toxicology and Applied Pharmacology|May 11, 2025

Protective effect of empagliflozin against paracetamol-induced acute kidney injury through modulation of AMPK/SIRT1/PGC-1α pathway in experimental miceEsraa M Mosalam, Hind S AboShabaan, Marwa M Mahfouz, et al.

Bioorganic Chemistry|February 5, 2022

New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studiesSara A Darwish, Mohamed M El-Kerdawy, Ahmad R Elsheakh, et al.

European Journal of Medicinal Chemistry|July 12, 2023

2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profilingMoataz A Shaldam, Denisa Hendrychová, Radwan El-Haggar, et al.

Bioorganic Chemistry|October 11, 2025

Identification of isatin-triazole-benzenesulfonamide hybrids as dual hCA IX/XII and c-met inhibitors with hypoxia-mediated chemo-sensitizing activityWagdy M Eldehna, Mohamed R Elnagar, Simone Giovannuzzi, et al.

Pharmaceuticals (Basel, Switzerland)|September 23, 2022

Bilosomes as Nanoplatform for Oral Delivery and Modulated In Vivo Antimicrobial Activity of LycopeneReem Binsuwaidan, Amal A Sultan, Walaa A Negm, et al.

Journal of Medicinal Chemistry|December 16, 2022

Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo EvaluationsAhmed A Al-Karmalawy, Mohamed S Nafie, Moataz A Shaldam, et al.

Drug Development Research|June 18, 2026

Identification of Quinoline Tethered Thiadiazole/Thiazole Derivatives as Potent Tyrosinase Inhibitors With Promising Anti-Toxoplasma gondii Agents: Design, Synthesis, and Computational AnalysisAhmed Sabt, Maciej Chyb, Aladdin M Srour, et al.

Bioorganic Chemistry|August 25, 2023

Novel 4-(2-arylidenehydrazineyl)thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico insightsHeba A Elsebaie, Eman A El-Bastawissy, Kamel M Elberembally, et al.

Plos One|March 8, 2024

DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-RasTaghreed A Majrashi, Ahmed Sabt, Hadia Almahli, et al.

Bioorganic Chemistry|January 6, 2024

Development of new thieno[2,3-d]pyrimidines as dual EGFR and STAT3 inhibitors endowed with anticancer and pro-apoptotic activitiesHeba A Elsebaie, Tarek F El-Moselhy, Eman A El-Bastawissy, et al.

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Showing results (31-40 of 72) with videos related to

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Pageof 8

Toxicology and Applied Pharmacology|May 11, 2025

Protective effect of empagliflozin against paracetamol-induced acute kidney injury through modulation of AMPK/SIRT1/PGC-1α pathway in experimental miceEsraa M Mosalam, Hind S AboShabaan, Marwa M Mahfouz, et al.

Bioorganic Chemistry|February 5, 2022

New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studiesSara A Darwish, Mohamed M El-Kerdawy, Ahmad R Elsheakh, et al.

European Journal of Medicinal Chemistry|July 12, 2023

2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profilingMoataz A Shaldam, Denisa Hendrychová, Radwan El-Haggar, et al.

Bioorganic Chemistry|October 11, 2025

Identification of isatin-triazole-benzenesulfonamide hybrids as dual hCA IX/XII and c-met inhibitors with hypoxia-mediated chemo-sensitizing activityWagdy M Eldehna, Mohamed R Elnagar, Simone Giovannuzzi, et al.

Pharmaceuticals (Basel, Switzerland)|September 23, 2022

Bilosomes as Nanoplatform for Oral Delivery and Modulated In Vivo Antimicrobial Activity of LycopeneReem Binsuwaidan, Amal A Sultan, Walaa A Negm, et al.

Journal of Medicinal Chemistry|December 16, 2022

Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo EvaluationsAhmed A Al-Karmalawy, Mohamed S Nafie, Moataz A Shaldam, et al.

Drug Development Research|June 18, 2026

Identification of Quinoline Tethered Thiadiazole/Thiazole Derivatives as Potent Tyrosinase Inhibitors With Promising Anti-Toxoplasma gondii Agents: Design, Synthesis, and Computational AnalysisAhmed Sabt, Maciej Chyb, Aladdin M Srour, et al.

Bioorganic Chemistry|August 25, 2023

Novel 4-(2-arylidenehydrazineyl)thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico insightsHeba A Elsebaie, Eman A El-Bastawissy, Kamel M Elberembally, et al.

Plos One|March 8, 2024

DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-RasTaghreed A Majrashi, Ahmed Sabt, Hadia Almahli, et al.

Bioorganic Chemistry|January 6, 2024

Development of new thieno[2,3-d]pyrimidines as dual EGFR and STAT3 inhibitors endowed with anticancer and pro-apoptotic activitiesHeba A Elsebaie, Tarek F El-Moselhy, Eman A El-Bastawissy, et al.

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