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Journal of Enzyme Inhibition and Medicinal Chemistry|May 1, 2023
Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitorsMoataz A Shaldam, Hadia Almahli, Andrea Angeli, et al.European Journal of Medicinal Chemistry|May 29, 2024
A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessmentsSalma M Hefny, Tarek F El-Moselhy, Nabaweya El-Din, et al.Bioorganic Chemistry|July 16, 2024
Unveiling the potential of isatin-grafted phenyl-1,2,3-triazole derivatives as dual VEGFR-2/STAT-3 inhibitors: Design, synthesis and biological assessmentsHeba A Elsebaie, Maha-Hamadien Abdulla, Zainab M Elsayed, et al.RSC Medicinal Chemistry|February 6, 2026
Design, synthesis, and molecular modeling of novel thiazolopyridine-based inhibitors of enoyl acyl carrier protein reductase (InhA) as anti-Mycobacterium tuberculosis agentsAhmed Sabt, Małgorzata Korycka-Machała, Asmaa F Kassem, et al.RSC Medicinal Chemistry|March 3, 2025
Donepezil-based rational design of N-substituted quinazolinthioacetamide candidates as potential acetylcholine esterase inhibitors for the treatment of Alzheimer's disease: in vitro and in vivo studiesAhmed A Al-Karmalawy, Ahmed F Mohamed, Heba Nasr Shalaby, et al.Drug Development Research|May 28, 2026
Molecular Boomerangs Against Cancer: Design, Synthesis, Biological Evaluation, and In Silico Study of Novel Dual PARP-1/EGFR InhibitorsHaytham O Tawfik, Amr Tayel, Salma M Hefny, et al.Pharmaceuticals (Basel, Switzerland)|November 27, 2025
Development of New Pyrazolo [3,4-b]Pyridine Derivatives as Potent Anti-Leukemic Agents and Topoisomerase IIα Inhibitors with Broad-Spectrum CytotoxicityWagdy M Eldehna, Haytham O Tawfik, Denisa Veselá, et al.European Journal of Medicinal Chemistry|February 24, 2023
Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studiesAhmed H E Hassan, Kazem Mahmoud, Trong-Nhat Phan, et al.Journal of Medicinal Chemistry|April 16, 2025
Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII InhibitorsMohamed A Zeidan, Mahmoud Abdelrahman Alkabbani, Simone Giovannuzzi, et al.Journal of Medicinal Chemistry|January 11, 2024
Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of GlaucomaHaytham O Tawfik, Mohamed M Saleh, Andrea Ammara, et al.Pageof 8