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Molecular Metabolism|February 18, 2019
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in miceDaniel Lindén, Andrea Ahnmark, Piero Pingitore, et al.Nature|September 14, 2018
In vivo CRISPR editing with no detectable genome-wide off-target mutationsPinar Akcakaya, Maggie L Bobbin, Jimmy A Guo, et al.Nature Communications|September 30, 2020
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discoveryAnders Lundin, Michelle J Porritt, Himjyot Jaiswal, et al.Nature Communications|September 6, 2023
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivoBurcu Bestas, Sandra Wimberger, Dmitrii Degtev, et al.Diabetes|August 8, 2013
Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesityStefania Carobbio, Rachel M Hagen, Christopher J Lelliott, et al.Nature Communications|October 14, 2022
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitisKasparas Petkevicius, Henrik Palmgren, Matthew S Glover, et al.Plos Biology|November 9, 2006
Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performanceChristopher J Lelliott, Gema Medina-Gomez, Natasa Petrovic, et al.Nature Communications|August 14, 2023
Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editingSandra Wimberger, Nina Akrap, Mike Firth, et al.The EMBO Journal|February 6, 2016
Mitochondria are required for pro-ageing features of the senescent phenotypeClara Correia-Melo, Francisco D M Marques, Rhys Anderson, et al.Nature Metabolism|February 20, 2020
IDOL regulates systemic energy balance through control of neuronal VLDLR expressionStephen D Lee, Christina Priest, Mikael Bjursell, et al.Pageof 9