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Chemical Biology & Drug Design|October 5, 2023
Targeted modification of furan-2-carboxaldehydes into Michael acceptor analogs yielded long-acting hemoglobin modulators with dual antisickling activitiesAbdelsattar M Omar, Osheiza Abdulmalik, Khalid M El-Say, et al.
Biochemistry|November 20, 2015
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO BiochemistryGuoyan G Xu, Tanvi M Deshpande, Mohini S Ghatge, et al.
Plos One|August 11, 2012
Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibitionAmit K Gandhi, Jigar V Desai, Mohini S Ghatge, et al.
Pharmaceuticals (Basel, Switzerland)|June 27, 2025
Michael Acceptor Compounds as Hemoglobin Oxygen Affinity Modulators for Reversing Sickling of Red Blood CellsKhadijah A Mohammad, Asala H Naghi, Mohini S Ghatge, et al.
Biochimica Et Biophysica Acta|January 7, 2015
Molecular basis of E. coli L-threonine aldolase catalytic inactivation at low pHSoumya G Remesh, Mohini S Ghatge, Mostafa H Ahmed, et al.
Plos One|August 1, 2012
Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinaseMohini S Ghatge, Roberto Contestabile, Martino L di Salvo, et al.
The FEBS Journal|September 21, 2023
Functional and structural properties of pyridoxal reductase (PdxI) from Escherichia coli: a pivotal enzyme in the vitamin B6 salvage pathwayAngela Tramonti, Akua K Donkor, Alessia Parroni, et al.
Biomolecules|May 28, 2022
Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell DiseaseRana T Alhashimi, Mohini S Ghatge, Akua K Donkor, et al.
Scientific Reports|November 21, 2020
VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditionsOsheiza Abdulmalik, Piyusha P Pagare, Boshi Huang, et al.
Acta Crystallographica. Section D, Biological Crystallography|November 22, 2011
Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillinOsheiza Abdulmalik, Mohini S Ghatge, Faik N Musayev, et al.
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