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Chemmedchem|January 21, 2022
Covalent Fragment Screening Identifies Rgl2 RalGEF Cysteine for Targeted Covalent Inhibition of Ral GTPase ActivationKhuchtumur Bum-Erdene, Mona K Ghozayel, David Xu, et al.
ACS Chemical Biology|April 8, 2026
Degradation of the TEAD·YAP/TAZ Transcription Factor Complex by Heterobifunctional Small Molecules That Bind to the TEAD Allosteric Lipid PocketI-Ju Yeh, Mona K Ghozayel, Khuchtumur Bum-Erdene, et al.
Biorxiv : the Preprint Server for Biology|January 16, 2026
Degradation of the TEAD•YAP/TAZ Transcription Factor Complex by Heterobifunctional Small Molecules that Bind to the TEAD Allosteric Lipid PocketI-Ju Yeh, Mona K Ghozayel, Khuchtumur Bum-Erdene, et al.
ACS Medicinal Chemistry Letters|January 25, 2021
Design and Synthesis of Fragment Derivatives with a Unique Inhibition Mechanism of the uPAR·uPA InteractionKhuchtumur Bum-Erdene, Degang Liu, David Xu, et al.
Biorxiv : the Preprint Server for Biology|March 27, 2026
A Fragment Screen Identifies Acrylamide Covalent Inhibitors of the TEAD•YAP Protein-Protein InteractionKhuchtumur Bum-Erdene, Mona K Ghozayel, Mark J Zhang, et al.
ACS Chemical Biology|August 27, 2025
Small-Molecule Covalent Stabilization and Inhibition of the TEAD·YAP1 Transcription Factor in Cancer CellsI-Ju Yeh, Khuchtumur Bum-Erdene, Mona K Ghozayel, et al.
RSC Medicinal Chemistry|September 21, 2023
Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEAD·YAP1 interactionKhuchtumur Bum-Erdene, Mona K Ghozayel, Mark J Zhang, et al.
Chemmedchem|September 30, 2017
Mimicking Intermolecular Interactions of Tight Protein-Protein Complexes for Small-Molecule AntagonistsDavid Xu, Khuchtumur Bum-Erdene, Yubing Si, et al.
Chemmedchem|October 27, 2020
Small-Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational SelectionDavid Xu, Khuchtumur Bum-Erdene, Julie M Leth, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 18, 2020
Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPasesKhuchtumur Bum-Erdene, Degang Liu, Giovanni Gonzalez-Gutierrez, et al.
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