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Cell Reports|September 23, 2014
Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewalAnetta Ptasinska, Salam A Assi, Natalia Martinez-Soria, et al.
Iscience|April 19, 2024
Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1Daniel J L Coleman, Peter Keane, Paulynn S Chin, et al.
Cancer Cell|November 16, 2016
Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic LeukemiaShan Lin, Roger T Luo, Anetta Ptasinska, et al.
Genes & Development|August 5, 2008
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory elementAlexander K Ebralidze, Florence C Guibal, Ulrich Steidl, et al.
Nature Communications|February 14, 2024
Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growthSophie G Kellaway, Sandeep Potluri, Peter Keane, et al.
Cell Reports|July 28, 2015
Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin SignaturePierre Cauchy, Sally R James, Joaquin Zacarias-Cabeza, et al.
The EMBO Journal|August 30, 2011
RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory elementElena Levantini, Sanghoon Lee, Hanna S Radomska, et al.
Developmental Cell|March 1, 2016
Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and DifferentiationDebbie K Goode, Nadine Obier, M S Vijayabaskar, et al.
Cancer Cell|November 5, 2013
Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaHong Zhang, Meritxell Alberich-Jorda, Giovanni Amabile, et al.
Cancer Cell|September 25, 2018
Prospective Isolation and Characterization of Genetically and Functionally Distinct AML SubclonesBauke de Boer, Janine Prick, Maurien G Pruis, et al.
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