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Molecular Oncology|April 5, 2021
KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrixJin K Kim, Michael R Marco, Seo-Hyun Choi, et al.Cancer Cell|April 16, 2015
AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomasMoshe Elkabets, Evangelos Pazarentzos, Dejan Juric, et al.Science Signaling|March 27, 2014
Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancerJessica J Tao, Pau Castel, Nina Radosevic-Robin, et al.Cancer Research|February 8, 2023
Mutated HRAS Activates YAP1-AXL Signaling to Drive Metastasis of Head and Neck CancerSankar Jagadeeshan, Manu Prasad, Mai Badarni, et al.Nature Communications|May 14, 2024
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolismTal Levy, Kai Voeltzke, Laura Hruby, et al.Journal for Immunotherapy of Cancer|March 16, 2022
MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancerManu Prasad, Jonathan Zorea, Sankar Jagadeeshan, et al.Cancer Discovery|October 2, 2020
TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase InhibitorsEmiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, et al.The Journal of Clinical Investigation|September 24, 2025
USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancerNishi Kumari, Sarah Ce Wright, Christopher M Witham, et al.Pageof 9