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Research Square|April 2, 2024
Nonpathogenic E. coli engineered to surface display cytokines as a new platform for immunotherapyShaobo Yang, Michal Sheffer, Isabel E Kaplan, et al.Nature Biotechnology|October 4, 2024
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responsesShaobo Yang, Michal Sheffer, Isabel E Kaplan, et al.Journal of Hematology & Oncology|February 13, 2025
First-in-human evaluation of memory-like NK cells with an IL-15 super-agonist and CTLA-4 blockade in advanced head and neck cancerRoman M Shapiro, Michal Sheffer, Matthew A Booker, et al.Science Advances|July 12, 2024
CAR memory-like NK cells targeting the membrane proximal domain of mesothelin demonstrate promising activity in ovarian cancerMubin Tarannum, Khanhlinh Dinh, Juliana Vergara, et al.The Journal of Clinical Investigation|March 29, 2022
Expansion, persistence, and efficacy of donor memory-like NK cells infused for posttransplant relapseRoman M Shapiro, Grace C Birch, Guangan Hu, et al.Cancer Immunology Research|June 9, 2022
Activation of Tumor-Cell STING Primes NK-Cell TherapyErik H Knelson, Elena V Ivanova, Mubin Tarannum, et al.Cancer Cell|March 6, 2026
Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancerMarco Campisi, Tatsuya Osaki, Ian Dryg, et al.Pageof 3