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Bioorganic & Medicinal Chemistry Letters|August 20, 2013
Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonistsJames E Sheppeck, John L Gilmore, Hai-Yun Xiao, et al.Bioorganic & Medicinal Chemistry Letters|August 2, 2016
Discovery and SAR of pyrrolo[2,1-f][1,2,4]triazin-4-amines as potent and selective PI3Kδ inhibitorsRajeev S Bhide, James Neels, Lan-Ying Qin, et al.Journal of Medicinal Chemistry|April 24, 2015
Improving the pharmacokinetic and CYP inhibition profiles of azaxanthene-based glucocorticoid receptor modulators-identification of (S)-5-(2-(9-fluoro-2-(4-(2-hydroxypropan-2-yl)phenyl)-5H-chromeno[2,3-b]pyridin-5-yl)-2-methylpropanamido)-N-(tetrahydro-2H-pyran-4-yl)-1,3,4-thiadiazole-2-carboxamide (BMS-341)Michael G Yang, T G Murali Dhar, Zili Xiao, et al.Bioorganic & Medicinal Chemistry Letters|August 3, 2020
Discovery of (3S,4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonistsBin Jiang, James J-W Duan, Sylwia Stachura, et al.Bioorganic & Medicinal Chemistry Letters|June 11, 2013
The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding modeStephen T Wrobleski, Shuqun Lin, T G Murali Dhar, et al.ACS Medicinal Chemistry Letters|September 18, 2020
Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P1) Modulators: Optimization of the PK, PD, and Safety ProfilesZili Xiao, Michael G Yang, T G Murali Dhar, et al.Journal of Medicinal Chemistry|June 26, 2007
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)Scott H Watterson, Ping Chen, Yufen Zhao, et al.Journal of Medicinal Chemistry|December 2, 1999
Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinonesD Nagarathnam, S W Miao, B Lagu, et al.ACS Medicinal Chemistry Letters|December 18, 2020
Novel Tricyclic Pyroglutamide Derivatives as Potent RORγt Inverse Agonists Identified using a Virtual Screening ApproachQingjie Liu, Douglas G Batt, Carolyn A Weigelt, et al.Bioorganic & Medicinal Chemistry Letters|January 22, 2017
Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitorsLan-Ying Qin, Zheming Ruan, Robert J Cherney, et al.Pageof 10