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Murali Gopalakrishnan

Showing results (71-80 of 83) with videos related to

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Journal of Medicinal Chemistry|December 13, 2006
Effects of substitution on 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a dihydropyridine ATP-sensitive potassium channel openerRobert J Altenbach, Michael E Brune, Steven A Buckner, et al.
Journal of Biomolecular Screening|November 14, 2006
Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonistsJun Chen, Marc R Lake, Reza S Sabet, et al.
Journal of Medicinal Chemistry|May 8, 2009
Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptorRamin Faghih, Sujatha M Gopalakrishnan, Jens Halvard Gronlien, et al.
Journal of the American Society of Nephrology : JASN|August 23, 2017
Targeting Anti-TGF-<i>β</i> Therapy to Fibrotic Kidneys with a Dual Specificity Antibody ApproachSteve McGaraughty, Rachel A Davis-Taber, Chang Z Zhu, et al.
British Journal of Pharmacology|August 11, 2004
In vitro and in vivo characterization of a novel naphthylamide ATP-sensitive K+ channel opener, A-151892Murali Gopalakrishnan, Steven A Buckner, Char-Chang Shieh, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 18, 2002
(-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. I. In vitro characterizationMurali Gopalakrishnan, Steven A Buckner, Kristi L Whiteaker, et al.
Journal of Medicinal Chemistry|May 28, 2004
Synthesis and structure-activity relationships of a novel series of tricyclic dihydropyridine-based KATP openers that potently inhibit bladder contractions in vitroWilliam A Carroll, Konstantinos A Agrios, Robert J Altenbach, et al.
CNS Drug Reviews|June 5, 2004
ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disordersLynne E Rueter, David J Anderson, Clark A Briggs, et al.
Biochemical Pharmacology|May 31, 2011
Potentiation of analgesic efficacy but not side effects: co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in ratsChang Z Zhu, Chih-Liang Chin, Nathan R Rustay, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 28, 2007
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathwaysRobert S Bitner, William H Bunnelle, David J Anderson, et al.
Pageof 9

Showing results (71-80 of 83) with videos related to

Sort By:
Pageof 9
Journal of Medicinal Chemistry|December 13, 2006
Effects of substitution on 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a dihydropyridine ATP-sensitive potassium channel openerRobert J Altenbach, Michael E Brune, Steven A Buckner, et al.
Journal of Biomolecular Screening|November 14, 2006
Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonistsJun Chen, Marc R Lake, Reza S Sabet, et al.
Journal of Medicinal Chemistry|May 8, 2009
Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptorRamin Faghih, Sujatha M Gopalakrishnan, Jens Halvard Gronlien, et al.
Journal of the American Society of Nephrology : JASN|August 23, 2017
Targeting Anti-TGF-<i>β</i> Therapy to Fibrotic Kidneys with a Dual Specificity Antibody ApproachSteve McGaraughty, Rachel A Davis-Taber, Chang Z Zhu, et al.
British Journal of Pharmacology|August 11, 2004
In vitro and in vivo characterization of a novel naphthylamide ATP-sensitive K+ channel opener, A-151892Murali Gopalakrishnan, Steven A Buckner, Char-Chang Shieh, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 18, 2002
(-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. I. In vitro characterizationMurali Gopalakrishnan, Steven A Buckner, Kristi L Whiteaker, et al.
Journal of Medicinal Chemistry|May 28, 2004
Synthesis and structure-activity relationships of a novel series of tricyclic dihydropyridine-based KATP openers that potently inhibit bladder contractions in vitroWilliam A Carroll, Konstantinos A Agrios, Robert J Altenbach, et al.
CNS Drug Reviews|June 5, 2004
ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disordersLynne E Rueter, David J Anderson, Clark A Briggs, et al.
Biochemical Pharmacology|May 31, 2011
Potentiation of analgesic efficacy but not side effects: co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in ratsChang Z Zhu, Chih-Liang Chin, Nathan R Rustay, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 28, 2007
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathwaysRobert S Bitner, William H Bunnelle, David J Anderson, et al.
Pageof 9