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Muthiah Manoharan

Showing results (101-110 of 172) with videos related to

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Nucleic Acids Research|September 21, 2007
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzymeFeng Li, Pradeep S Pallan, Martin A Maier, et al.
ACS Chemical Biology|April 26, 2013
Lipid nanoparticles improve activity of single-stranded siRNA and gapmer antisense oligonucleotides in animalsThazha P Prakash, Walt F Lima, Heather M Murray, et al.
The Journal of Organic Chemistry|February 9, 2011
Versatile site-specific conjugation of small molecules to siRNA using click chemistryTakeshi Yamada, Chang Geng Peng, Shigeo Matsuda, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society|February 23, 2010
Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS deliveryQingmin Chen, David Butler, William Querbes, et al.
Journal of the American Chemical Society|August 22, 2012
Branched multifunctional polyether polyketals: variation of ketal group structure enables unprecedented control over polymer degradation in solution and within cellsRajesh A Shenoi, Jayaprakash K Narayanannair, Jasmine L Hamilton, et al.
European Journal of Biochemistry|May 25, 2002
Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay. Discovery of selective and potent inhibitors of glutathione S-transferase Mu expressionPeter A C 't Hoen, Bram-Sieben Rosema, Jan N M Commandeur, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|February 20, 2018
Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA ConjugatesDonald J Foster, Christopher R Brown, Sarfraz Shaikh, et al.
Nucleic Acids Research|October 14, 2021
Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAsMark K Schlegel, Shigeo Matsuda, Christopher R Brown, et al.
The Journal of Organic Chemistry|March 5, 2016
Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified OligonucleotidesAlexander V Kel'in, Ivan Zlatev, Joel Harp, et al.
Cell|March 27, 2007
miR-181a is an intrinsic modulator of T cell sensitivity and selectionQi-Jing Li, Jacqueline Chau, Peter J R Ebert, et al.
Pageof 18

Showing results (101-110 of 172) with videos related to

Sort By:
Pageof 18
Nucleic Acids Research|September 21, 2007
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzymeFeng Li, Pradeep S Pallan, Martin A Maier, et al.
ACS Chemical Biology|April 26, 2013
Lipid nanoparticles improve activity of single-stranded siRNA and gapmer antisense oligonucleotides in animalsThazha P Prakash, Walt F Lima, Heather M Murray, et al.
The Journal of Organic Chemistry|February 9, 2011
Versatile site-specific conjugation of small molecules to siRNA using click chemistryTakeshi Yamada, Chang Geng Peng, Shigeo Matsuda, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society|February 23, 2010
Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS deliveryQingmin Chen, David Butler, William Querbes, et al.
Journal of the American Chemical Society|August 22, 2012
Branched multifunctional polyether polyketals: variation of ketal group structure enables unprecedented control over polymer degradation in solution and within cellsRajesh A Shenoi, Jayaprakash K Narayanannair, Jasmine L Hamilton, et al.
European Journal of Biochemistry|May 25, 2002
Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay. Discovery of selective and potent inhibitors of glutathione S-transferase Mu expressionPeter A C 't Hoen, Bram-Sieben Rosema, Jan N M Commandeur, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|February 20, 2018
Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA ConjugatesDonald J Foster, Christopher R Brown, Sarfraz Shaikh, et al.
Nucleic Acids Research|October 14, 2021
Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAsMark K Schlegel, Shigeo Matsuda, Christopher R Brown, et al.
The Journal of Organic Chemistry|March 5, 2016
Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified OligonucleotidesAlexander V Kel'in, Ivan Zlatev, Joel Harp, et al.
Cell|March 27, 2007
miR-181a is an intrinsic modulator of T cell sensitivity and selectionQi-Jing Li, Jacqueline Chau, Peter J R Ebert, et al.
Pageof 18