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Muthiah Manoharan

Showing results (111-120 of 172) with videos related to

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Nature Biotechnology|September 18, 2007
Mechanisms and optimization of in vivo delivery of lipophilic siRNAsChristian Wolfrum, Shuanping Shi, K Narayanannair Jayaprakash, et al.
Journal of Medicinal Chemistry|April 14, 2006
Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acidsMartin A Maier, Christine C Esau, Andrew M Siwkowski, et al.
Biochemistry|July 2, 2014
Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAsJiaxin Hu, Jing Liu, K Jayaprakash Narayanannair, et al.
Nucleic Acids Research|August 15, 2018
Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activityJoel M Harp, Dale C Guenther, Anna Bisbe, et al.
Journal of Medicinal Chemistry|January 30, 2018
Facile Synthesis, Geometry, and 2'-Substituent-Dependent in Vivo Activity of 5'-(E)- and 5'-(Z)-Vinylphosphonate-Modified siRNA ConjugatesRubina Giare Parmar, Christopher R Brown, Shigeo Matsuda, et al.
Journal of the American Chemical Society|October 7, 2024
Single-Stranded Hairpin Loop RNAs (loopmeRNAs) Potently Induce Gene Silencing through the RNA Interference PathwayKrishna C Aluri, Dhrubajyoti Datta, Scott Waldron, et al.
RNA (New York, N.Y.)|January 8, 2003
Selection of antisense oligodeoxynucleotides against glutathione S-transferase MuPeter A C 't Hoen, Ruud Out, Jan N M Commandeur, et al.
Nucleic Acids Research|March 15, 2020
Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonucleasePawan Kumar, Rohan Degaonkar, Dale C Guenther, et al.
Nucleic Acids Research|July 9, 2010
Modulation of thermal stability can enhance the potency of siRNAHaripriya Addepalli, Meena, Chang G Peng, et al.
Journal of the American Chemical Society|June 2, 2017
Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNAMark K Schlegel, Donald J Foster, Alexander V Kel'in, et al.
Pageof 18

Showing results (111-120 of 172) with videos related to

Sort By:
Pageof 18
Nature Biotechnology|September 18, 2007
Mechanisms and optimization of in vivo delivery of lipophilic siRNAsChristian Wolfrum, Shuanping Shi, K Narayanannair Jayaprakash, et al.
Journal of Medicinal Chemistry|April 14, 2006
Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acidsMartin A Maier, Christine C Esau, Andrew M Siwkowski, et al.
Biochemistry|July 2, 2014
Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAsJiaxin Hu, Jing Liu, K Jayaprakash Narayanannair, et al.
Nucleic Acids Research|August 15, 2018
Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activityJoel M Harp, Dale C Guenther, Anna Bisbe, et al.
Journal of Medicinal Chemistry|January 30, 2018
Facile Synthesis, Geometry, and 2'-Substituent-Dependent in Vivo Activity of 5'-(E)- and 5'-(Z)-Vinylphosphonate-Modified siRNA ConjugatesRubina Giare Parmar, Christopher R Brown, Shigeo Matsuda, et al.
Journal of the American Chemical Society|October 7, 2024
Single-Stranded Hairpin Loop RNAs (loopmeRNAs) Potently Induce Gene Silencing through the RNA Interference PathwayKrishna C Aluri, Dhrubajyoti Datta, Scott Waldron, et al.
RNA (New York, N.Y.)|January 8, 2003
Selection of antisense oligodeoxynucleotides against glutathione S-transferase MuPeter A C 't Hoen, Ruud Out, Jan N M Commandeur, et al.
Nucleic Acids Research|March 15, 2020
Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonucleasePawan Kumar, Rohan Degaonkar, Dale C Guenther, et al.
Nucleic Acids Research|July 9, 2010
Modulation of thermal stability can enhance the potency of siRNAHaripriya Addepalli, Meena, Chang G Peng, et al.
Journal of the American Chemical Society|June 2, 2017
Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNAMark K Schlegel, Donald J Foster, Alexander V Kel'in, et al.
Pageof 18