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Journal of Controlled Release : Official Journal of the Controlled Release Society
|
March 15, 2023
Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors
Shubaash Anthiya, Süleyman Can Öztürk, Hamdullah Yanik, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
February 18, 2021
Centyrin ligands for extrahepatic delivery of siRNA
Donna Klein, Shalom Goldberg, Christopher S Theile, et al.
Nature Communications
|
February 21, 2018
Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity
Maja M Janas, Mark K Schlegel, Carole E Harbison, et al.
Nucleic Acids Research
|
July 16, 2021
Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo
Hartmut Jahns, Nate Taneja, Jennifer L S Willoughby, et al.
Nucleic Acids Research
|
February 12, 2021
siRNAs containing 2'-fluorinated Northern-methanocarbacyclic (2'-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2'-F-NMC NTPs
Masaaki Akabane-Nakata, Namrata D Erande, Pawan Kumar, et al.
Journal of Medicinal Chemistry
|
February 3, 2025
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3' End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain
Rajat S Das, Dhrubajyoti Datta, Christopher R Brown, et al.
Nucleic Acids Research
|
September 11, 2021
Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing
Hartmut Jahns, Rohan Degaonkar, Peter Podbevsek, et al.
Chembiochem : a European Journal of Chemical Biology
|
March 20, 2015
Hepatocyte-specific delivery of siRNAs conjugated to novel non-nucleosidic trivalent N-acetylgalactosamine elicits robust gene silencing in vivo
Kallanthottathil G Rajeev, Jayaprakash K Nair, Muthusamy Jayaraman, et al.
Nucleic Acids Research
|
April 17, 2026
Acyclic serinol nucleic acid modification of siRNAs overcomes seed region mediated off-target effects while maintaining potency
Tyler Chickering, Joel M Harp, Yongfeng Jiang, et al.
RNA (New York, N.Y.)
|
February 2, 2012
Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo
Donald J Foster, Scott Barros, Rick Duncan, et al.
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of 18
Search research articles
Search
Showing results (131-140 of 172) with videos related to
Sort By:
Page
of 18
Journal of Controlled Release : Official Journal of the Controlled Release Society
|
March 15, 2023
Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors
Shubaash Anthiya, Süleyman Can Öztürk, Hamdullah Yanik, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
February 18, 2021
Centyrin ligands for extrahepatic delivery of siRNA
Donna Klein, Shalom Goldberg, Christopher S Theile, et al.
Nature Communications
|
February 21, 2018
Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity
Maja M Janas, Mark K Schlegel, Carole E Harbison, et al.
Nucleic Acids Research
|
July 16, 2021
Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo
Hartmut Jahns, Nate Taneja, Jennifer L S Willoughby, et al.
Nucleic Acids Research
|
February 12, 2021
siRNAs containing 2'-fluorinated Northern-methanocarbacyclic (2'-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2'-F-NMC NTPs
Masaaki Akabane-Nakata, Namrata D Erande, Pawan Kumar, et al.
Journal of Medicinal Chemistry
|
February 3, 2025
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3' End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain
Rajat S Das, Dhrubajyoti Datta, Christopher R Brown, et al.
Nucleic Acids Research
|
September 11, 2021
Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing
Hartmut Jahns, Rohan Degaonkar, Peter Podbevsek, et al.
Chembiochem : a European Journal of Chemical Biology
|
March 20, 2015
Hepatocyte-specific delivery of siRNAs conjugated to novel non-nucleosidic trivalent N-acetylgalactosamine elicits robust gene silencing in vivo
Kallanthottathil G Rajeev, Jayaprakash K Nair, Muthusamy Jayaraman, et al.
Nucleic Acids Research
|
April 17, 2026
Acyclic serinol nucleic acid modification of siRNAs overcomes seed region mediated off-target effects while maintaining potency
Tyler Chickering, Joel M Harp, Yongfeng Jiang, et al.
RNA (New York, N.Y.)
|
February 2, 2012
Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo
Donald J Foster, Scott Barros, Rick Duncan, et al.
Page
of 18