Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Muthiah Manoharan

Showing results (141-150 of 172) with videos related to

Pageof 18
Sort By:
Molecular Therapy. Nucleic Acids|December 19, 2013
Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid NanoparticlesBarbara L Mui, Ying K Tam, Muthusamy Jayaraman, et al.
Antimicrobial Agents and Chemotherapy|June 10, 2009
RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategyRene Alvarez, Sayda Elbashir, Todd Borland, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|October 10, 2017
Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor ExpressionJennifer L S Willoughby, Amy Chan, Alfica Sehgal, et al.
ACS Chemical Biology|March 3, 2015
siRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytesShigeo Matsuda, Kristofer Keiser, Jayaprakash K Nair, et al.
Journal of Medicinal Chemistry|October 14, 2005
Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acidKlaus Albertshofer, Andrew M Siwkowski, Edward V Wancewicz, et al.
Chembiochem : a European Journal of Chemical Biology|April 29, 2016
5'-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc ConjugatesRubina Parmar, Jennifer L S Willoughby, Jingxuan Liu, et al.
Nature Nanotechnology|December 6, 2019
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugsAkin Akinc, Martin A Maier, Muthiah Manoharan, et al.
Journal of the American Chemical Society|September 23, 2017
4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene SilencingElise Malek-Adamian, Dale C Guenther, Shigeo Matsuda, et al.
Nature Nanotechnology|June 5, 2012
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA deliveryHyukjin Lee, Abigail K R Lytton-Jean, Yi Chen, et al.
Angewandte Chemie (International Ed. in English)|July 12, 2012
Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivoMuthusamy Jayaraman, Steven M Ansell, Barbara L Mui, et al.
Pageof 18

Showing results (141-150 of 172) with videos related to

Sort By:
Pageof 18
Molecular Therapy. Nucleic Acids|December 19, 2013
Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid NanoparticlesBarbara L Mui, Ying K Tam, Muthusamy Jayaraman, et al.
Antimicrobial Agents and Chemotherapy|June 10, 2009
RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategyRene Alvarez, Sayda Elbashir, Todd Borland, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|October 10, 2017
Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor ExpressionJennifer L S Willoughby, Amy Chan, Alfica Sehgal, et al.
ACS Chemical Biology|March 3, 2015
siRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytesShigeo Matsuda, Kristofer Keiser, Jayaprakash K Nair, et al.
Journal of Medicinal Chemistry|October 14, 2005
Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acidKlaus Albertshofer, Andrew M Siwkowski, Edward V Wancewicz, et al.
Chembiochem : a European Journal of Chemical Biology|April 29, 2016
5'-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc ConjugatesRubina Parmar, Jennifer L S Willoughby, Jingxuan Liu, et al.
Nature Nanotechnology|December 6, 2019
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugsAkin Akinc, Martin A Maier, Muthiah Manoharan, et al.
Journal of the American Chemical Society|September 23, 2017
4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene SilencingElise Malek-Adamian, Dale C Guenther, Shigeo Matsuda, et al.
Nature Nanotechnology|June 5, 2012
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA deliveryHyukjin Lee, Abigail K R Lytton-Jean, Yi Chen, et al.
Angewandte Chemie (International Ed. in English)|July 12, 2012
Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivoMuthusamy Jayaraman, Steven M Ansell, Barbara L Mui, et al.
Pageof 18