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Muthiah Manoharan

Showing results (31-40 of 172) with videos related to

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The Journal of Organic Chemistry|January 19, 2002
Synthesis of 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl] modified nucleosides and oligonucleotidesThazha P Prakash, Andrew M Kawasaki, Allister S Fraser, et al.
The Journal of Gene Medicine|September 24, 2004
Towards a therapeutic inhibition of dystrophin exon 23 splicing in mdx mouse muscle induced by antisense oligoribonucleotides (splicomers): target sequence optimisation using oligonucleotide arraysIan R Graham, Vanessa J Hill, Muthiah Manoharan, et al.
ACS Central Science|December 31, 2025
C‑Nucleosides Stabilize RNA by Reducing Nucleophilicity at 2'-OHDipanwita Banerjee, Lu Xiao, Pavitra S Thacker, et al.
Nucleic Acids Research|February 25, 2011
Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytesErich Koller, Thomas M Vincent, Alfred Chappell, et al.
Organic Letters|February 14, 2003
2'-O-[2-(amino)-2-oxoethyl] oligonucleotidesThazha P Prakash, Andrew M Kawasaki, Elena A Lesnik, et al.
JCI Insight|November 8, 2023
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulatorsKostas C Nikolaou, Svenja Godbersen, Muthiah Manoharan, et al.
Chemistry & Biology|December 21, 2010
Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoterMasayuki Matsui, Fuminori Sakurai, Sayda Elbashir, et al.
Chembiochem : a European Journal of Chemical Biology|December 5, 2002
Improving antisense oligonucleotide binding to human serum albumin: dramatic effect of ibuprofen conjugationMuthiah Manoharan, Gopal B Inamati, Elena A Lesnik, et al.
Nucleic Acids Research|February 6, 2004
2'-O-[2-[(N,N-dimethylamino)oxy]ethyl]-modified oligonucleotides inhibit expression of mRNA in vitro and in vivoThazha P Prakash, Joseph F Johnston, Mark J Graham, et al.
Organic Letters|June 7, 2003
2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effectsMarija Prhavc, Thazha P Prakash, George Minasov, et al.
Pageof 18

Showing results (31-40 of 172) with videos related to

Sort By:
Pageof 18
The Journal of Organic Chemistry|January 19, 2002
Synthesis of 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl] modified nucleosides and oligonucleotidesThazha P Prakash, Andrew M Kawasaki, Allister S Fraser, et al.
The Journal of Gene Medicine|September 24, 2004
Towards a therapeutic inhibition of dystrophin exon 23 splicing in mdx mouse muscle induced by antisense oligoribonucleotides (splicomers): target sequence optimisation using oligonucleotide arraysIan R Graham, Vanessa J Hill, Muthiah Manoharan, et al.
ACS Central Science|December 31, 2025
C‑Nucleosides Stabilize RNA by Reducing Nucleophilicity at 2'-OHDipanwita Banerjee, Lu Xiao, Pavitra S Thacker, et al.
Nucleic Acids Research|February 25, 2011
Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytesErich Koller, Thomas M Vincent, Alfred Chappell, et al.
Organic Letters|February 14, 2003
2'-O-[2-(amino)-2-oxoethyl] oligonucleotidesThazha P Prakash, Andrew M Kawasaki, Elena A Lesnik, et al.
JCI Insight|November 8, 2023
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulatorsKostas C Nikolaou, Svenja Godbersen, Muthiah Manoharan, et al.
Chemistry & Biology|December 21, 2010
Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoterMasayuki Matsui, Fuminori Sakurai, Sayda Elbashir, et al.
Chembiochem : a European Journal of Chemical Biology|December 5, 2002
Improving antisense oligonucleotide binding to human serum albumin: dramatic effect of ibuprofen conjugationMuthiah Manoharan, Gopal B Inamati, Elena A Lesnik, et al.
Nucleic Acids Research|February 6, 2004
2'-O-[2-[(N,N-dimethylamino)oxy]ethyl]-modified oligonucleotides inhibit expression of mRNA in vitro and in vivoThazha P Prakash, Joseph F Johnston, Mark J Graham, et al.
Organic Letters|June 7, 2003
2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effectsMarija Prhavc, Thazha P Prakash, George Minasov, et al.
Pageof 18