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The EMBO Journal|November 18, 2006
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathwayAkihito Nakajima, Sachiko Komazawa-Sakon, Mutsuhiro Takekawa, et al.
Nature Communications|December 3, 2022
ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase IISeina Ohe, Yuji Kubota, Kiyoshi Yamaguchi, et al.
The Journal of Antibiotics|September 7, 2017
A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2Masatomi Iijima, Yuji Kubota, Ryuichi Sawa, et al.
Plos One|September 22, 2011
Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinomaMotoyuki Otsuka, Akemi Takata, Takeshi Yoshikawa, et al.
Cancer Science|November 19, 2017
Downregulation of dual-specificity phosphatase 4 enhances cell proliferation and invasiveness in colorectal carcinomasMichihiro Ichimanda, Naoki Hijiya, Yoshiyuki Tsukamoto, et al.
Current Biology : CB|April 29, 2023
Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspasesDaichi Fujikawa, Takanori Nakamura, Daisuke Yoshioka, et al.
Nature Communications|July 13, 2022
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancerYuji Kubota, Yuko Fujioka, Ashwini Patil, et al.
The EMBO Journal|July 26, 2003
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell deathSachiko Sakon, Xin Xue, Mutsuhiro Takekawa, et al.
Nature Structural & Molecular Biology|February 17, 2015
Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificityYusuke Sato, Eiji Goto, Yuri Shibata, et al.
Life Science Alliance|September 2, 2025
Amino acid-dependent TSC2 dephosphorylation by lysosome-PP2A regulates mTORC1 signaling transductionTakanori Nakamura, Shigeyuki Nada, Masaki Matsumoto, et al.
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