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Journal of Medicinal Chemistry|December 23, 2021
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar ActivityDavid Steadman, Benjamin N Atkinson, Yuguang Zhao, et al.Medchemcomm|September 20, 2019
Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screenBenjamin N Atkinson, David Steadman, Yuguang Zhao, et al.Bioorganic & Medicinal Chemistry Letters|December 22, 2019
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitorsBenjamin N Atkinson, David Steadman, William Mahy, et al.Cancer Research|March 5, 2003
The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancerJanos L Tanyi, Andrew J Morris, Judith K Wolf, et al.Journal of Medicinal Chemistry|April 13, 2001
Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamidesJ B Thomas, X M Herault, R B Rothman, et al.Journal of Medicinal Chemistry|August 10, 2001
Identification of the first trans-(3R,4R)- dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid kappa receptor antagonist activityJ B Thomas, R N Atkinson, R B Rothman, et al.American Journal of Clinical Oncology|February 6, 2004
Second malignancies after chemotherapy and radiotherapy for Hodgkin diseaseGregory M Chronowski, Richard B Wilder, Larry B Levy, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 29, 2000
Clinical and biological effects of intraperitoneal injections of recombinant interferon-gamma and recombinant interleukin 2 with or without tumor-infiltrating lymphocytes in patients with ovarian or peritoneal carcinomaR S Freedman, A P Kudelka, J J Kavanagh, et al.The Medical Journal of Australia|December 2, 2006
Tackling the burden of injury in Australasia: developing a binational trauma registryTamzyn M Davey, Cliff W Pollard, Leanne M Aitken, et al.Neuropharmacology|June 23, 2010
A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in ratsXu-Feng Zhang, Char-Chang Shieh, Mark L Chapman, et al.Pageof 23