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The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 28, 2014
Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosisAlyssa N Coyne, Bhavani Bagevalu Siddegowda, Patricia S Estes, et al.Acta Neuropathologica|November 29, 2023
G<sub>2</sub>C<sub>4</sub> targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neuronsJeffrey D Rothstein, Victoria Baskerville, Sampath Rapuri, et al.Cell Reports|March 31, 2021
UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunctionBenjamin L Zaepfel, Zhe Zhang, Kirstin Maulding, et al.Biorxiv : the Preprint Server for Biology|January 16, 2026
Identification of molecular and clinical ALS subgroups based on TDP-43 loss of function molecular markers from population-based patient-derived iPS motor neuronsTrinity Cheng, Shaili Tripathi, Yike Guo, et al.Cell Reports|October 6, 2017
Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALSAlyssa N Coyne, Ileana Lorenzini, Ching-Chieh Chou, et al.Neuron|July 17, 2020
G<sub>4</sub>C<sub>2</sub> Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTDAlyssa N Coyne, Benjamin L Zaepfel, Lindsey Hayes, et al.Cell|April 10, 2018
Stress Granule Assembly Disrupts Nucleocytoplasmic TransportKe Zhang, J Gavin Daigle, Kathleen M Cunningham, et al.Human Molecular Genetics|September 20, 2015
Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translationAlyssa N Coyne, Shizuka B Yamada, Bhavani Bagevalu Siddegowda, et al.Neuron|October 8, 2019
CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG TranslationWeiwei Cheng, Shaopeng Wang, Zhe Zhang, et al.Nature Neuroscience|February 25, 2025
Neuronal polyunsaturated fatty acids are protective in ALS/FTDAshling Giblin, Alexander J Cammack, Niek Blomberg, et al.Pageof 4