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Biochemical Pharmacology|September 14, 1993
NADPH-dependent enzyme-catalyzed reduction of aldophosphamide, the pivotal metabolite of cyclophosphamideH K Parekh, N E SladekBiochemical Pharmacology|October 1, 1985
Sensitivity of murine B- and T-lymphocytes to oxazaphosphorine and non-oxazaphosphorine nitrogen mustardsP C Smith, N E SladekBiochemical Pharmacology|October 1, 1985
Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorinesF R Kohn, N E SladekImmunopharmacology and Immunotoxicology|January 1, 1988
Ex vivo treatment of murine splenocyte-supplemented bone marrow inocula with mafosfamide prior to allogeneic transplantation in an attempt to prevent lethal graft-versus-host disease without compromising engraftmentF R Kohn, N E SladekCancer Chemotherapy and Pharmacology|January 1, 1997
Multienzyme-mediated stable and transient multidrug resistance and collateral sensitivity induced by xenobioticsG K Rekha, N E SladekCancer Research|April 1, 1985
Restoration of sensitivity to oxazaphosphorines by inhibitors of aldehyde dehydrogenase activity in cultured oxazaphosphorine-resistant L1210 and cross-linking agent-resistant P388 cell linesN E Sladek, G J LandkamerBiochemical Pharmacology|January 7, 1993
Sensitivity of aldehyde dehydrogenases in murine tumor and hematopoietic progenitor cells to inhibition by chloral hydrate as determined by the ability of chloral hydrate to potentiate the cytotoxic action of mafosfamideP A Maki, N E SladekCancer Research|August 15, 1991
Potentiation of the cytotoxic action of mafosfamide by N-isopropyl-p-formylbenzamide, a metabolite of procarbazineP A Maki, N E SladekBiochemical Pharmacology|July 15, 1988
Kinetic characterization of the catalysis of "activated" cyclophosphamide (4-hydroxycyclophosphamide/aldophosphamide) oxidation to carboxyphosphamide by mouse hepatic aldehyde dehydrogenasesC L Manthey, N E SladekBiochemical Pharmacology|November 16, 1994
Intrinsic cellular resistance to oxazaphosphorines exhibited by a human colon carcinoma cell line expressing relatively large amounts of a class-3 aldehyde dehydrogenaseG K Rekha, L Sreerama, N E SladekPageof 5