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The Biochemical Journal|January 12, 1999
Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinaseA M Conway, S Rakhit, S Pyne, et al.
The Journal of Biological Chemistry|July 18, 1997
The regulation of the cGMP-binding cGMP phosphodiesterase by proteins that are immunologically related to gamma subunit of the photoreceptor cGMP phosphodiesteraseA Lochhead, E Nekrasova, V Y Arshavsky, et al.
The Biochemical Journal|January 1, 1994
Bradykinin-dependent activation of adenylate cyclase activity and cyclic AMP accumulation in tracheal smooth muscle occurs via protein kinase C-dependent and -independent pathwaysP A Stevens, S Pyne, M Grady, et al.
The American Journal of Physiology|October 8, 1997
Sphingosine prevents diacylglycerol signaling to mitogen-activated protein kinase in airway smooth muscleD Tolan, A M Conway, N J Pyne, et al.
Cellular Signalling|October 12, 2000
The role of the cyclic GMP-inhibited cyclic AMP-specific phosphodiesterase (PDE3) in regulating clonal BRIN-BD11 insulin secreting cell survivalM Ahmad, P R Flatt, B L Furman, et al.
FEBS Letters|January 16, 1989
Treatment of intact hepatocytes with either the phorbol ester TPA or glucagon elicits the phosphorylation and functional inactivation of the inhibitory guanine nucleotide regulatory protein GiN J Pyne, G J Murphy, G Milligan, et al.
British Journal of Pharmacology|August 28, 2001
Assessment of agonism at G-protein coupled receptors by phosphatidic acid and lysophosphatidic acid in human embryonic kidney 293 cellsF Alderton, B Sambi, R Tate, et al.
The Biochemical Journal|August 1, 1989
Insulin stimulates the tyrosyl phosphorylation and activation of the 52 kDa peripheral plasma-membrane cyclic AMP phosphodiesterase in intact hepatocytesN J Pyne, W Cushley, H G Nimmo, et al.
Biochemical Society Transactions|October 26, 2005
Lipid phosphate phosphatases and lipid phosphate signallingS Pyne, J S Long, N T Ktistakis, et al.
European Journal of Pharmacology|April 18, 1997
The effect of selective phosphodiesterase inhibitors on plasma insulin concentrations and insulin secretion in vitro in the ratM El-Metwally, R Shafiee-Nick, N J Pyne, et al.
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