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Journal of Medicinal Chemistry|June 23, 2006
Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin bindingGeorge S Sheppard, Jieyi Wang, Megumi Kawai, et al.Cell Death & Disease|January 16, 2015
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)J D Leverson, H Zhang, J Chen, et al.Bioorganic & Medicinal Chemistry Letters|April 22, 2018
Discovery and optimization of novel constrained pyrrolopyridone BET family inhibitorsSteven D Fidanze, Dachun Liu, Robert A Mantei, et al.Bioorganic & Medicinal Chemistry Letters|March 8, 2017
Methylpyrrole inhibitors of BET bromodomainsLisa A Hasvold, George S Sheppard, Le Wang, et al.Journal of Medicinal Chemistry|February 14, 2015
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivityMilan Bruncko, Le Wang, George S Sheppard, et al.Journal of Medicinal Chemistry|September 27, 2017
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain InhibitorKeith F McDaniel, Le Wang, Todd Soltwedel, et al.Nature|January 24, 2020
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancerEmily J Faivre, Keith F McDaniel, Daniel H Albert, et al.Journal of Medicinal Chemistry|April 4, 2017
Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain InhibitorsLe Wang, John K Pratt, Todd Soltwedel, et al.Aquatic Conservation : Marine and Freshwater Ecosystems|December 16, 2014
Reefs and islands of the Chagos Archipelago, Indian Ocean: why it is the world's largest no-take marine protected areaC R C Sheppard, M Ateweberhan, B W Bowen, et al.Nature|June 19, 2010
Size and albedo of Kuiper belt object 55636 from a stellar occultationJ L Elliot, M J Person, C A Zuluaga, et al.Pageof 22