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The Journal of Allergy and Clinical Immunology|July 14, 2016
X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) geneChantal Lagresle-Peyrou, Sonia Luce, Farid Ouchani, et al.
Science Translational Medicine|October 13, 2021
Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomasStefan R Sweha, Chan Chung, Siva Kumar Natarajan, et al.
Neuro-Oncology|December 19, 2024
Radiographic and visual response to the type II RAF inhibitor tovorafenib in children with relapsed/refractory optic pathway glioma in the FIREFLY-1 trialKarsten Nysom, Lindsay B Kilburn, Sarah E S Leary, et al.
Cancer Cell|December 3, 2015
MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing ChromatinMarco Gallo, Fiona J Coutinho, Robert J Vanner, et al.
Science (New York, N.Y.)|May 14, 2016
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscapeChao Lu, Siddhant U Jain, Dominik Hoelper, et al.
Cancer Discovery|September 24, 2020
H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of BoneSima Khazaei, Nicolas De Jay, Shriya Deshmukh, et al.
Biorxiv : the Preprint Server for Biology|December 20, 2023
H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programsBrian Krug, Bo Hu, Haifen Chen, et al.
Neuro-Oncology|May 19, 2026
TRAM-01: A phase 2 study of trametinib for pediatric patients with neurofibromatosis type 1 and plexiform neurofibromasDorsa Sadat Kiaei, Maxime Caru, Valérie Larouche, et al.
Nature Genetics|December 5, 2022
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomasSelin Jessa, Abdulshakour Mohammadnia, Ashot S Harutyunyan, et al.
Nature Communications|March 21, 2019
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesisAshot S Harutyunyan, Brian Krug, Haifen Chen, et al.
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