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EJNMMI Radiopharmacy and Chemistry|July 20, 2026
Synthesis and in vitro evaluation of pharmacokinetically optimized 99mTc-labeled cholecystokinin-2 receptor-targeted peptides for improved SPECT imagingVeronika Felber, Nadine Holzleitner, Thomas GüntherPharmaceuticals (Basel, Switzerland)|December 23, 2022
Introduction of a SiFA Moiety into the D-Glutamate Chain of DOTA-PP-F11N Results in Radiohybrid-Based CCK-2R-Targeted Compounds with Improved Pharmacokinetics In VivoNadine Holzleitner, Thomas Günther, Roswitha Beck, et al.EJNMMI Research|July 8, 2023
Investigation of the structure-activity relationship at the N-terminal part of minigastrin analogsNadine Holzleitner, Thomas Günther, Amira Daoud-Gadieh, et al.Pharmaceutics|March 29, 2023
Development of the First 18F-Labeled Radiohybrid-Based Minigastrin Derivative with High Target Affinity and Tumor Accumulation by Substitution of the Chelating MoietyThomas Günther, Nadine Holzleitner, Daniel Di Carlo, et al.EJNMMI Research|March 1, 2024
Significant reduction of activity retention in the kidneys via optimized linker sequences in radiohybrid-based minigastrin analogsNadine Holzleitner, Sebastian Fischer, Isabel Maniyankerikalam, et al.EJNMMI Radiopharmacy and Chemistry|February 5, 2026
Synthesis and preclinical development of a novel 68Ga/89Zr-Labelled ανβ6-integrin targeting trimerClemens Decristoforo, Giacomo Gariglio, Fernando A Patiño Álvarez, et al.Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|April 30, 2025
First-in-Human Serum Stability Studies of [177Lu]Lu-AMTG: A Step Toward Improved GRPR-Targeted Radiopharmaceutical TherapyVeronika Felber, Nadine Holzleitner, Markus Joksch, et al.Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|November 7, 2023
Preclinical Comparison of the 64Cu- and 68Ga-Labeled GRPR-Targeted Compounds RM2 and AMTG, as Well as First-in-Humans [68Ga]Ga-AMTG PET/CTLena Koller, Markus Joksch, Sarah Schwarzenböck, et al.Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|November 9, 2023
Preclinical Evaluation of Minigastrin Analogs and Proof-of-Concept [68Ga]Ga-DOTA-CCK-66 PET/CT in 2 Patients with Medullary Thyroid CancerThomas Günther, Nadine Holzleitner, Oliver Viering, et al.European Journal of Nuclear Medicine and Molecular Imaging|October 11, 2024
Preclinical evaluation of 225Ac-labeled minigastrin analog DOTA-CCK-66 for Targeted Alpha TherapyNadine Holzleitner, Meryl Vilangattil, Abir Swaidan, et al.Pageof 2