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Antimicrobial Agents and Chemotherapy|March 30, 2006
In vitro characterization of the antibacterial spectrum of novel bacterial type II topoisomerase inhibitors of the aminobenzimidazole classNagraj Mani, Christian H Gross, Jonathan D Parsons, et al.Antimicrobial Agents and Chemotherapy|November 23, 2006
Dual targeting of GyrB and ParE by a novel aminobenzimidazole class of antibacterial compoundsTrudy H Grossman, Douglas J Bartels, Steve Mullin, et al.Bioorganic & Medicinal Chemistry Letters|April 2, 2010
Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyraseSteven M Ronkin, Michael Badia, Steve Bellon, et al.Antimicrobial Agents and Chemotherapy|October 9, 2013
In vitro phenotypic characterization of hepatitis C virus NS3 protease variants observed in clinical studies of telaprevirMin Jiang, Nagraj Mani, Chao Lin, et al.Antimicrobial Agents and Chemotherapy|April 7, 2010
Characterization of V36C, a novel amino acid substitution conferring hepatitis C virus (HCV) resistance to telaprevir, a potent peptidomimetic inhibitor of HCV proteaseLaetitia Barbotte, Abdelhakim Ahmed-Belkacem, Stéphane Chevaliez, et al.Bioorganic & Medicinal Chemistry Letters|April 2, 2014
Successful application of serum shift prediction models to the design of dual targeting inhibitors of bacterial gyrase B and topoisomerase IV with improved in vivo efficacyEmanuele Perola, Dean Stamos, Anne-Laure Grillot, et al.RSC Medicinal Chemistry|April 18, 2022
The identification of highly efficacious functionalised tetrahydrocyclopenta[<i>c</i>]pyrroles as inhibitors of HBV viral replication through modulation of HBV capsid assemblyAndrew G Cole, Steven G Kultgen, Nagraj Mani, et al.Journal of Medicinal Chemistry|September 4, 2024
Rational Design, Synthesis, and Structure-Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836Andrew G Cole, Steven G Kultgen, Nagraj Mani, et al.ACS Medicinal Chemistry Letters|September 18, 2024
Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly ModulatorsEugen F Mesaros, Andrew G Cole, Steven G Kultgen, et al.ACS Medicinal Chemistry Letters|February 16, 2017
Discovery of Novel Allosteric HCV NS5B Inhibitors. 2. Lactam-Containing Thiophene CarboxylatesPan Li, Warren Dorsch, David J Lauffer, et al.Pageof 4