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Journal of Molecular Biology|June 11, 2002
Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteinsAnna Niedzwiecka, Joseph Marcotrigiano, Janusz Stepinski, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 4, 2010
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progressionLuc Furic, Liwei Rong, Ola Larsson, et al.
Nature Reviews. Disease Primers|September 30, 2017
Fragile X syndromeRandi J Hagerman, Elizabeth Berry-Kravis, Heather Cody Hazlett, et al.
JCI Insight|May 25, 2021
mRNA translation is a therapeutic vulnerability necessary for bladder epithelial transformationSujata Jana, Rucha Deo, Rowan P Hough, et al.
The Journal of Clinical Investigation|August 15, 2024
MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunctionNatalie M Walker, Yuta Ibuki, A Patrick McLinden, et al.
Nature Communications|March 4, 2025
PARP inhibitor radiosensitization enhances anti-PD-L1 immunotherapy through stabilizing chemokine mRNA in small cell lung cancerXiaozhuo Ran, Bell Xi Wu, Venkatasubramanian Vidhyasagar, et al.
Nature Neuroscience|April 28, 2015
Light-regulated translational control of circadian behavior by eIF4E phosphorylationRuifeng Cao, Christos G Gkogkas, Nuria de Zavalia, et al.
Redox Biology|February 19, 2026
4E-BP inhibition ameliorates heart failure through translational upregulation of SERCA2a and modulation of mitochondrial redox signaling in cardiomyocytesJunling Gao, Ting Lan, Xin Xu, et al.
Science (New York, N.Y.)|May 29, 2010
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPsRyan J O Dowling, Ivan Topisirovic, Tommy Alain, et al.
Oncotarget|September 9, 2017
Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cellsMamatha Bhat, Akiko Yanagiya, Tyson Graber, et al.
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