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Blood|January 11, 2024
Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancyJiuyang Liu, Shuran Li, Qin Wang, et al.Frontiers in Cell and Developmental Biology|November 8, 2021
Periphery Biomarkers for Objective Diagnosis of Cognitive Decline in Type 2 Diabetes PatientsYanchao Liu, Shujuan Zhang, Benrong He, et al.Neuroimage. Clinical|July 12, 2021
PET evidence of preclinical cerebellar amyloid plaque deposition in autosomal dominant Alzheimer's disease-causing Presenilin-1 E280A mutation carriersValentina Ghisays, Francisco Lopera, Dhruman D Goradia, et al.Journal of Medicinal Chemistry|May 2, 2024
Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl-2Yunhang Guo, Hai Xue, Nan Hu, et al.Communications Biology|January 17, 2025
An atlas of neuropathic pain-associated molecular pathological characteristics in the mouse spinal cordFu-Lu Dong, Lina Yu, Pei-Da Feng, et al.Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|February 1, 2022
Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia TrialClara Vila-Castelar, Pierre N Tariot, Kaycee M Sink, et al.Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|May 18, 2020
Baseline demographic, clinical, and cognitive characteristics of the Alzheimer's Prevention Initiative (API) Autosomal-Dominant Alzheimer's Disease Colombia TrialSilvia Rios-Romenets, Francisco Lopera, Kaycee M Sink, et al.Nature Genetics|September 11, 2012
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactionsChen Wu, Peter Kraft, Kan Zhai, et al.Journal of Medicinal Chemistry|August 6, 2019
Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine KinaseYunhang Guo, Ye Liu, Nan Hu, et al.Journal of Medicinal Chemistry|March 13, 2023
Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase for B-Cell Malignancies and Autoimmune DiseasesYunhang Guo, Nan Hu, Ye Liu, et al.Pageof 142